Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.
Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …
development, although existing evidence for this varies. We present a meta-analysis and …
Pubertal development and regulation
Puberty marks the end of childhood and is a period when individuals undergo physiological
and psychological changes to achieve sexual maturation and fertility. The hypothalamic …
and psychological changes to achieve sexual maturation and fertility. The hypothalamic …
An atlas of genetic correlations across human diseases and traits
Identifying genetic correlations between complex traits and diseases can provide useful
etiological insights and help prioritize likely causal relationships. The major challenges …
etiological insights and help prioritize likely causal relationships. The major challenges …
Exposure to perfluorinated alkyl substances and health outcomes in children: a systematic review of the epidemiologic literature
Perfluoroalkyl substances (PFAS), chemicals used to make products stain and stick
resistant, have been linked to health effects in adults and adverse birth outcomes. A growing …
resistant, have been linked to health effects in adults and adverse birth outcomes. A growing …
Timing of puberty in boys and girls: A population‐based study
N Brix, A Ernst, LLB Lauridsen, E Parner… - Paediatric and …, 2019 - Wiley Online Library
Background A secular trend towards earlier puberty has been observed in girls, while a
similar trend has been more uncertain in boys. We estimated current ages at pubertal …
similar trend has been more uncertain in boys. We estimated current ages at pubertal …
Developmental adaptation to stress: An evolutionary perspective
BJ Ellis, M Del Giudice - Annual review of psychology, 2019 - annualreviews.org
The assumption that early stress leads to dysregulation and impairment is widespread in
developmental science and informs prevailing models (eg, toxic stress). An alternative …
developmental science and informs prevailing models (eg, toxic stress). An alternative …
Interaction between gut microbiota and sex hormones and their relation to sexual dimorphism in metabolic diseases
JA Santos-Marcos, M Mora-Ortiz… - Biology of sex …, 2023 - Springer
Metabolic diseases, such as obesity, metabolic syndrome (MetS) and type 2 diabetes (T2D),
are now a widespread pandemic in the developed world. These pathologies show sex …
are now a widespread pandemic in the developed world. These pathologies show sex …
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
FR Day, DJ Thompson, H Helgason, DI Chasman… - Nature …, 2017 - nature.com
The timing of puberty is a highly polygenic childhood trait that is epidemiologically
associated with various adult diseases. Using 1000 Genomes Project–imputed genotype …
associated with various adult diseases. Using 1000 Genomes Project–imputed genotype …
Childhood obesity and central precocious puberty
L Shi, Z Jiang, L Zhang - Frontiers in endocrinology, 2022 - frontiersin.org
Childhood obesity is a major public health problem worldwide, and the relationship between
obesity and central precocious puberty has long been confirmed, however, the mechanisms …
obesity and central precocious puberty has long been confirmed, however, the mechanisms …
Childhood overweight and obesity and timing of puberty in boys and girls: cohort and sibling-matched analyses
N Brix, A Ernst, LLB Lauridsen… - International journal …, 2020 - academic.oup.com
Background Early puberty is a risk indicator for adult diseases. Identification of modifiable
causes of earlier puberty is, therefore, warranted. We estimate the association between …
causes of earlier puberty is, therefore, warranted. We estimate the association between …