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Background Noise-induced hearing loss is one of the most common forms of sensorineural
hearing loss, is a major health problem, is largely preventable and is probably more …

The noise-induced and age-related loss of synaptic connections between auditory-nerve
fibers and cochlear hair cells is well-established from histopathology in several mammalian …

The classic view of sensorineural hearing loss has been that the primary damage targets are
hair cells and that auditory nerve loss is typically secondary to hair cell degeneration …

Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Cochlear synaptopathy can result from various insults, including acoustic trauma, aging,
ototoxicity, or chronic conductive hearing loss. For example, moderate noise exposure in …

This study tested hypothesized relationships between noise exposure and auditory deficits.
Both retrospective assessment of potential associations between noise exposure history and …

Cochlear synaptopathy is the noise-induced or age-related loss of ribbon synapses between
inner hair cells (IHCs) and auditory-nerve fibers (ANFs), first reported in CBA/CaJ mice …

Acquired sensorineural hearing loss is one of the most prevalent chronic diseases, and
aging and acoustic overexposure are common contributors. Decades of study in animals …

An estimate of lifetime noise exposure was used as the primary predictor of performance on
a range of behavioral tasks: frequency and intensity difference limens, amplitude modulation …