Abstract Linear Energy Transfer (LET) is widely used to express the radiation quality of ion
beams, when characterizing the biological effectiveness. However, averaged LET may be …

Clinical treatment with protons uses the concept of relative biological effectiveness (RBE) to
convert the absorbed dose into an RBE-weighted dose that equals the dose for radiotherapy …

The linear-quadratic model is one of the key tools in radiation biology and physics. It
provides a simple relationship between cell survival and delivered dose:, and has been …

In this review article, we review the 3 important aspects of linear-energy-transfer (LET) in
intensity-modulated proton therapy (IMPT) for head and neck (H&N) cancer management …

Recently, a number of clinical studies have explored links between possible Relative
Biological Effectiveness (RBE) elevations and patient toxicities and/or image changes …

Ionizing radiation is a common tool in medical procedures. Monte Carlo (MC) techniques are
widely used when dosimetry is the matter of investigation. The scientific community has …

Proton therapy is increasingly being used as a radiation therapy modality. There is
uncertainty about the biological effectiveness of protons relative to photon therapies as it …

Simple Summary The increasing global demand and accessibility for proton beam therapy
has been fueled by its recognised clinical benefits over traditional radiotherapy, primarily its …

Purpose To develop and validate combined ion-beam with constant relative biological
effectiveness (RBE)(CICR) particle therapy in single field arrangements for improved …

Dose in proton radiotherapy is generally prescribed by scaling the physical proton dose by a
constant value of 1.1. Relative biological effectiveness (RBE) is defined as the ratio of doses …