Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

The discovery of reciprocal connections between the central nervous system, sleep and the
immune system has shown that sleep enhances immune defences and that afferent signals …

From asthma and heart disease to diabetes and obesity, the human microbiome plays a role
in the pathogenesis of each chronic health condition plaguing today's society. Recent work …

Sleep represents an emergent set of many physiologic processes under primarily
neurobiological regulation that impact many physiologic systems. As such, many advances …

Background Sleep disturbance is associated with inflammatory disease risk and all-cause
mortality. Here, we assess global evidence linking sleep disturbance, sleep duration, and …

Background Environmental and lifestyle changes, in addition to the ageing of populations,
are generally believed to account for the rapid global increase in type 2 diabetes prevalence …

Sleep disturbances including insomnia independently contribute to risk of inflammatory
disorders and major depressive disorder. This review and overview provides an integrated …

Sleep is highly conserved across evolution, suggesting vital biological functions that are yet
to be fully understood. Animals and humans experiencing partial sleep restriction usually …

Sleep and exercise influence each other through complex, bilateral interactions that involve
multiple physiological and psychological pathways. Physical activity is usually considered …

Various lifestyle and environmental factors are known to influence sleep. Increasingly,
evidence points to a role for the microbiota in regulating brain and behaviour. This article …