The inflammatory process plays a significant role in the development of colon cancer (CRC).
Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation …

The intestinal immune system has the difficult task of protecting a large environmentally
exposed single layer of epithelium from pathogens without allowing inappropriate …

Background Macrophages are one of the most important players in the tumor
microenvironment. The polarization status of tumor associated macrophages into a pro …

Background & Aims The liver is one of the organs most commonly affected by metastasis.
The presence of liver metastases has been reported to be responsible for an …

Colorectal Cancer (CRC) ranks third in terms of incidence and second in terms of mortality
and prevalence worldwide. In relation to chemotherapy treatment, the most used drug is 5 …

Inflammation contributes to colon cancer initiation. The disease along with allergy and
autoimmunity has been on the rise in Western and more recently in developing countries …

The tumor microenvironment includes a complex network of immune T-cell subsets that play
important roles in colorectal cancer (CRC) progression and are key elements of CRC …

Simple Summary The gastrointestinal tumor microenvironment is regulated by cytokine
production from the tumor and adjacent immune cells. G-CSFR is a cytokine that is highly …

Background: We investigated whether preoperative and postoperative levels of inflammation
markers, which have mechanistically been linked to colorectal cancer progression, were …

Every colon cancer has its own unique characteristics, and therefore may respond differently
to identical treatments. Here, we develop a data driven mathematical model for the …