SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

Nrf2/Keap1/ARE signaling: Towards specific regulation

AV Ulasov, AA Rosenkranz, GP Georgiev, AS Sobolev - Life Sciences, 2022 - Elsevier
The Nrf2 transcription factor governs the expression of hundreds genes involved in cell
defense against oxidative stress, the hallmark of numerous diseases such as …

Neutrophil Extracellular Traps (NETs) and Covid-19: A new frontiers for therapeutic modality

HM Al-Kuraishy, AI Al-Gareeb, HA Al-Hussaniy… - International …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (Covid-19) is a worldwide infectious disease caused by
severe acute respiratory coronavirus 2 (SARS-CoV-2). In severe SARS-CoV-2 infection …

A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection

DA Jamison Jr, S Anand Narayanan… - European Journal of …, 2022 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has claimed approximately 5 million lives
and 257 million cases reported globally. This virus and disease have significantly affected …

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets

A Fodor, B Tiperciuc, C Login… - Oxidative medicine …, 2021 - Wiley Online Library
The outbreak of the COVID‐19 pandemic represents an ongoing healthcare emergency
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …

Thiol-mediated uptake

Q Laurent, R Martinent, B Lim, AT Pham, T Kato… - Jacs Au, 2021 - ACS Publications
This Perspective focuses on thiol-mediated uptake, that is, the entry of substrates into cells
enabled by oligochalcogenides or mimics, often disulfides, and inhibited by thiol-reactive …

[HTML][HTML] Lipid peroxidation as a hallmark of severity in COVID-19 patients

M Martín-Fernández, R Aller, M Heredia-Rodríguez… - Redox Biology, 2021 - Elsevier
Background Oxidative stress may be a key player in COVID-19 pathogenesis due to its
significant role in response to infections. A defective redox balance has been related to viral …

Metabolic implications of oxidative stress and inflammatory process in SARS-CoV-2 pathogenesis: therapeutic potential of natural antioxidants

GE Forcados, A Muhammad, OO Oladipo… - Frontiers in Cellular …, 2021 - frontiersin.org
COVID-19 is a zoonotic disease with devastating economic and public health impacts
globally. Being a novel disease, current research is focused on a clearer understanding of …

Vitamin C and cardiovascular disease: an update

MB Morelli, J Gambardella, V Castellanos, V Trimarco… - Antioxidants, 2020 - mdpi.com
The potential beneficial effects of the antioxidant properties of vitamin C have been
investigated in a number of pathological conditions. In this review, we assess both clinical …

COVID‐19 is getting on our nerves: sympathetic neural activity and haemodynamics in young adults recovering from SARS‐CoV‐2

NL Stute, JL Stickford, VM Province… - The Journal of …, 2021 - Wiley Online Library
Key points The impact of SARS‐CoV‐2 infection on autonomic and cardiovascular function
in otherwise healthy individuals is unknown. For the first time it is shown that young adults …