Oxidative stress and glutathione in TGF-β-mediated fibrogenesis

RM Liu, KAG Pravia - Free Radical Biology and Medicine, 2010 - Elsevier
Transforming growth factor β (TGF-β) is the most potent and ubiquitous profibrogenic
cytokine, and its expression is increased in almost all the fibrotic diseases and in …

Treatment of rheumatoid arthritis-associated interstitial lung disease: lights and shadows

G Cassone, A Manfredi, C Vacchi, F Luppi… - Journal of Clinical …, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disease affecting 0.5–1%
of the population worldwide. Interstitial lung disease (ILD) is a serious pulmonary …

[HTML][HTML] The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee …

L Gallelli, O Galasso, D Falcone, S Southworth… - Osteoarthritis and …, 2013 - Elsevier
Objective We investigated the effects of celecoxib, diclofenac, and ibuprofen on the disease-
specific quality of life, synovial fluid cytokines and signal transduction pathways in …

Macrophages in allergic asthma: fine-tuning their pro-and anti-inflammatory actions for disease resolution

AP Moreira, CM Hogaboam - Journal of Interferon & Cytokine …, 2011 - liebertpub.com
Macrophages exert prominent effects in the defense of the respiratory tract from airborne
pathogens. These cells are specialized to recognize, phagocytose, and destroy these …

Chronic venous leg ulcers are associated with high levels of metalloproteinases‐9 and neutrophil gelatinase‐associated lipocalin

R Serra, G Buffone, D Falcone… - Wound Repair and …, 2013 - Wiley Online Library
Venous ulcers are related to dysfunctions in extracellular matrix. Both matrix
metalloproteinases (MMP) and neutrophil gelatinase‐associated lipocalin (NGAL) could …

Anti-IL-6 treatment for inflammatory bowel diseases: next cytokine, next target

M Allocca, M Jovani, G Fiorino, S Schreiber… - Current drug …, 2013 - ingentaconnect.com
Inflammatory bowel diseases (IBD) are chronic, relapsing, and destructive inflammatory
disorders of the gastrointestinal tract. Both Crohn's disease (CD) and ulcerative colitis (UC) …

Rheumatoid arthritis related interstitial lung disease

A Manfredi, G Cassone, F Luppi… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Interstitial lung disease (ILD) represents a frequent extra-articular manifestation
of rheumatoid arthritis (RA) deeply impacting both quality of life and overall prognosis. Areas …

Ketogenic diet and microRNAs linked to antioxidant biochemical homeostasis

R Cannataro, MC Caroleo, A Fazio, C La Torre… - Antioxidants, 2019 - mdpi.com
Recently, we demonstrated the capability of the ketogenic diet (KD) to influence the
microRNA (miR) expression profile. Here, we report that KD is able to normalize miR …

Effects of transforming growth factor-β1 and vascular endothelial growth factor 165 gene transfer on Achilles tendon healing

Y Hou, ZB Mao, XL Wei, L Lin, LX Chen, HJ Wang… - Matrix Biology, 2009 - Elsevier
Repaired Achilles tendons typically take weeks before they are strong enough to handle
physiological loads. Gene therapy is a promising treatment for Achilles tendon defects. The …

Doxycycline speeds up healing of chronic venous ulcers

R Serra, L Gallelli, G Buffone, V Molinari… - International Wound …, 2015 - Wiley Online Library
Venous ulcers are common, with an overall prevalence of up to 2% in the general
population of western countries, and have significant socioeconomic impact. Matrix …