[HTML][HTML] DNA methyltransferase inhibition promotes recruitment of myeloid-derived suppressor cells to the tumor microenvironment through induction of tumor cell …
S Traynor, MG Terp, AY Nielsen, P Guldberg… - Cancer letters, 2023 - Elsevier
DNA methyltransferase (DNMT) inhibitors are used for treatment of certain hematological
malignancies and exert anti-cancer activity through diverse mechanisms, including …
malignancies and exert anti-cancer activity through diverse mechanisms, including …
[HTML][HTML] Natural killer cell activity in metastatic castration resistant prostate cancer patients treated with enzalutamide
AH Zedan, L Nederby, LM Volmer, CV Madsen… - Scientific Reports, 2023 - nature.com
Metastatic castration resistant prostate cancer (mCRPC) is still the lethal stage for the whole
spectrum of prostate cancer disease. Even though different treatment options have been …
spectrum of prostate cancer disease. Even though different treatment options have been …
[HTML][HTML] Initial Myeloid Cell Status Is Associated with Clinical Outcomes of Renal Cell Carcinoma
S Sabrina, Y Takeda, T Kato, S Naito, H Ito, Y Takai… - Biomedicines, 2023 - mdpi.com
The therapeutic outcome of immune checkpoint inhibition (ICI) can be improved through
combination treatments with ICI therapy. Myeloid-derived suppressor cells (MDSCs) strongly …
combination treatments with ICI therapy. Myeloid-derived suppressor cells (MDSCs) strongly …
去势抵抗性前列腺癌免疫微环境的研究现状与治疗方向
杨文博， 张斌， 吴佳慧， 崔洁 - 中国癌症杂志, 2023 - china-oncology.com
随着肿瘤免疫学的快速发展, 越来越多的研究关注肿瘤微环境中的免疫细胞和信号分子的作用.
前列腺癌是全球男性发病率第二的恶性肿瘤. 随着我国人口老龄化和筛查率的提高 …
前列腺癌是全球男性发病率第二的恶性肿瘤. 随着我国人口老龄化和筛查率的提高 …
The convergence of tumor suppressors on the type I interferon pathway in clear cell renal cell carcinoma and its therapeutic implications
LE Langbein, R El Hajjar, WY Kim… - American Journal of …, 2022 - journals.physiology.org
In clear cell renal cell carcinoma (ccRCC), the von Hippel–Lindau tumor suppressor
gene/hypoxia inducible factor (VHL/HIF) axis lays the groundwork for tumorigenesis and is …
gene/hypoxia inducible factor (VHL/HIF) axis lays the groundwork for tumorigenesis and is …
Current status and treatment direction of the immune microenvironment of castration-resistant prostate cancer
Y Wenbo, Z Bin, WU Jiahui, CUI Jie - China Oncology, 2023 - china-oncology.com
With the rapid development of cancer immunology, more and more research focuses on the
role of immune cells and signaling molecules in the tumor microenvironment. Prostate …
role of immune cells and signaling molecules in the tumor microenvironment. Prostate …
L'IFN-alpha secreto da macrofagi ingegnerizzati in vivo riduce le metastasi al fegato e induce l'attivazione di processi contro regolatori che ne limitano l'efficacia
T Kerzel - 2022 - iris.unisr.it
The liver hosts an immune suppressive environment, favoring metastatic seeding and
proliferation of cancer cells. Pharmacological treatments, including immunotherapies, fail in …
proliferation of cancer cells. Pharmacological treatments, including immunotherapies, fail in …