Interplay between mechanics and signalling in regulating cell fate

H De Belly, EK Paluch, KJ Chalut - Nature Reviews Molecular Cell …, 2022 - nature.com
Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

Insight into cellular uptake and intracellular trafficking of nanoparticles

P Foroozandeh, AA Aziz - Nanoscale research letters, 2018 - Springer
Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …

Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance

M Bionaz, E Vargas-Bello-Pérez, S Busato - Journal of Animal Science …, 2020 - Springer
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …

Multifaceted cargo recruitment and release from artificial membraneless organelles

J Liu, F Zhorabek, T Zhang, JWY Lam, BZ Tang… - Small, 2022 - Wiley Online Library
Liquid‐liquid phase separation (LLPS) drives membraneless organelles (MLOs) formation
for organizing biomolecules. Artificial MLOs (AMLOs) have been constructed mostly via the …

Bacterial membranes: structure, domains, and function

H Strahl, J Errington - Annual review of microbiology, 2017 - annualreviews.org
The bacterial cytoplasmic membrane is composed of roughly equal proportions of lipids and
proteins. The main lipid components are phospholipids, which vary in acyl chain length …

Defining raft domains in the plasma membrane

A Kusumi, TK Fujiwara, TA Tsunoyama, RS Kasai… - Traffic, 2020 - Wiley Online Library
Many plasma membrane (PM) functions depend on the cholesterol concentration in the PM
in strikingly nonlinear, cooperative ways: fully functional in the presence of physiological …

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain

JM Kefauver, M Hakala, L Zou, J Alba, J Espadas… - Nature, 2024 - nature.com
Biological membranes are partitioned into functional zones termed membrane
microdomains, which contain specific lipids and proteins,–. The composition and …

Lipid-based and protein-based interactions synergize transmembrane signaling stimulated by antigen clustering of IgE receptors

N Bag, A Wagenknecht-Wiesner… - Proceedings of the …, 2021 - National Acad Sciences
Antigen (Ag) crosslinking of immunoglobulin E–receptor (IgE-FcεRI) complexes in mast cells
stimulates transmembrane (TM) signaling, requiring phosphorylation of the clustered FcεRI …

[HTML][HTML] Atomic force microscopy to elucidate how peptides disrupt membranes

K Hammond, MG Ryadnov… - Biochimica et Biophysica …, 2021 - Elsevier
Atomic force microscopy is an increasingly attractive tool to study how peptides disrupt
membranes. Often performed on reconstituted lipid bilayers, it provides access to time and …

GPCRs in intracellular compartments: New targets for drug discovery

I Fasciani, M Carli, F Petragnano, F Colaianni, G Aloisi… - Biomolecules, 2022 - mdpi.com
The architecture of eukaryotic cells is defined by extensive membrane-delimited
compartments, which entails separate metabolic processes that would otherwise interfere …