Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …

Background In many countries of the industrialised world second generation ('atypical')
antipsychotics have become the first line drug treatment for people with schizophrenia. The …

Importance The American Medical Association has acknowledged the public health threat
posed by racism in medicine. While clinicians in psychiatry have echoed the sentiment, the …

The US is in the midst of an opioid epidemic. At the same time, tobacco use remains the
leading cause of preventable death and disability. While the shared biological …

Background Perphenazine is an old phenothiazine antipsychotic with a potency similar to
haloperidol. It has been used for many years and is popular in the northern European …

Leishmaniasis is a neglected tropical disease caused by Leishmania parasites and is
associated to more than 1.3 million cases annually. Some of the pharmacological options for …

Aims To investigate the impact of cytochrome P450 2D6 (CYP2D6) on dose‐adjusted serum
concentrations of flupentixol, haloperidol, perphenazine and zuclopenthixol in a therapeutic …

Solubility represents an important challenge for formulation of drugs, because the
therapeutic efficacy of a drug depends on the bioavailability and ultimately on its solubility …

Purpose To disentangle an association between tobacco smoking, smoking habits and
pharmacokinetic patterns such as plasma concentrations of risperidone (RIS), its active …

Background. Long‐acting injectable (LAI) antipsychotics are used as a monotherapy in
patients with schizophrenia. However, the combination of LAI and oral antipsychotics is …