Approximately 40% of treatments of chronic and recurrent osteomyelitis fail in part due to
bacterial persistence. Staphylococcus aureus, the predominant pathogen in human …

Over the last several decades, periprosthetic joint infection has been increasing in incidence
and is occurring in more complex patients. While there have been advances in both surgical …

Covering: 2016 to 2022 RNA polymerase (RNAP) is the central enzyme in bacterial gene
expression representing an attractive and validated target for antibiotics. Two well-known …

Rifamycins are widely used for treating mycobacterial and staphylococcal infections. Drug-
drug interactions (DDI) caused by rifampicin (RIF) are a major issue. We used a model …

Abstract Recently some borate bioactive glasses have been discovered to have an
antibacterial effect when interacting with pathogenic bacteria. In this study, borate bioactive …

Infective endocarditis (IE) is a rare but increasingly prevalent disease with high morbidity
and mortality, requiring antimicrobials and at times surgical intervention. Through the …

Background: Antimicrobial resistance is a major public health threat, and new agents are
needed. Computational approaches have been proposed to reduce the cost and time …

Staphylococcus aureus poses a significant threat as an opportunistic pathogen in humans,
and animal medicine, particularly in the context of hospital-acquired infections (HAIs) …

Staphylococcus aureus (S. aureus) is a major human pathogen and can cause a wide range
of diseases, including pneumonia, osteomyelitis, skin and soft tissue infections (SSTIs) …

Aims Although low-intensity pulsed ultrasound (LIPUS) combined with disinfectants has
been shown to effectively eliminate portions of biofilm in vitro, its efficacy in vivo remains …