Discoveries in fruit flies have greatly contributed to our understanding of neuroscience. The
use of an unparalleled wealth of tools, many of which originated between 1910–1960, has …

The intrinsic electrical properties and the synaptic input-output relationships of neurons are
governed by the action of voltage-dependent ion channels. The localization of specific …

Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

We have identified a conserved family of genes related to Drosophila eag, which encodes a
distinct type of voltage-activated K+ channel. Three related genes were recovered in …

TREK‐1 is a two‐pore‐domain background potassium channel expressed throughout the
central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. It …

A new human weakly inward rectifying K+ channel, TWIK‐1, has been isolated. This channel
is 336 amino acids long and has four transmembrane domains. Unlike other mammalian K+ …

Complementary DNAs (cDNAs) from mSlo, a gene encoding calcium-activated potassium
channels, were isolated from mouse brain and skeletal muscle, sequenced, and expressed …

Human TWIK‐1, which has been cloned recently, is a new structural type of weak inward
rectifier K+ channel. Here we report the structural and functional properties of TREK‐1, a …

With major oil spills in Korea, the United States, and China in the past decade, there has
been a dramatic increase in the number of studies characterizing the developmental toxicity …

▪ Abstract The intrinsic electrical properties of neurons are shaped in large part by the action
of voltage-gated ion channels. Molecular cloning studies have revealed a large family of ion …