Local drug delivery systems in the management of periodontitis: A scientific review

HR Rajeshwari, D Dhamecha, S Jagwani… - Journal of Controlled …, 2019 - Elsevier
Periodontitis (PD) is a microbial disease of tooth supporting tissues that results in
progressive destruction of surrounding soft and hard tissues with eventual tooth mobility and …

Local delivery and controlled release drugs systems: a new approach for the clinical treatment of periodontitis therapy

M Amato, S Santonocito, A Polizzi, GM Tartaglia… - Pharmaceutics, 2023 - mdpi.com
Periodontitis is an inflammatory disease of the gums characterized by the degeneration of
periodontal ligaments, the formation of periodontal pockets, and the resorption of the …

Dental delivery systems of antimicrobial drugs using chitosan, alginate, dextran, cellulose and other polysaccharides: A review

M Paul, SD Pramanik, RN Sahoo, YN Dey… - International Journal of …, 2023 - Elsevier
Dental caries, periodontal disease, and endodontic disease are major public health
concerns worldwide due to their impact on individuals' quality of life. The present problem of …

Co-delivery of minocycline and paclitaxel from injectable hydrogel for treatment of spinal cord injury

Z Nazemi, MS Nourbakhsh, S Kiani, Y Heydari… - Journal of controlled …, 2020 - Elsevier
Spinal cord injury (SCI) induces pathological and inflammatory responses that create an
inhibitory environment at the site of trauma, resulting in axonal degeneration and functional …

Near-Infrared-Enhanced Dual Enzyme-Mimicking Ag–TiO2–x@Alginate Microspheres with Antibactericidal and Oxygeneration Abilities to Treat Periodontitis

X Tan, S Liu, X Hu, R Zhang, X Su, R Qian… - … Applied Materials & …, 2022 - ACS Publications
The effective treatment for periodontitis is to completely and sustainedly eradicate the
bacterial pathogens from the complex periodontal pockets. Local sustained-release …

Layered biocompatible pH-responsive antibacterial composite film based on HNT/PLGA/chitosan for controlled release of minocycline as burn wound dressing

A Mohebali, M Abdouss - International Journal of Biological …, 2020 - Elsevier
In the present study, a promising pH-responsive wound dressing was prepared. Halloysite
nanotube (HNT) composites were modified with different concentration of both poly (lactic-co …

Local drug delivery systems for inflammatory diseases: Status quo, challenges, and opportunities

YC Chen, SF Gad, D Chobisa, Y Li, Y Yeo - Journal of Controlled Release, 2021 - Elsevier
Inflammation that is not resolved in due course becomes a chronic disease. The treatment of
chronic inflammatory diseases involves a long-term use of anti-inflammatory drugs such as …

[HTML][HTML] Bioresponsive nanotechnology in pediatric dental drug delivery

SE Alavi, L Malik, R Matti, F Al-Najafi… - Journal of Drug Delivery …, 2024 - Elsevier
Nanotechnology in the field of pediatric dentistry offers innovative solutions to challenges. In
this literature review, the nanomaterials application in dentistry, addressing critical concerns …

Biomimetic metal-organic nanoparticles prepared with a 3D-printed microfluidic device as a novel formulation for disulfiram-based therapy against breast cancer

Y Chang, J Jiang, W Chen, W Yang, L Chen… - Applied materials …, 2020 - Elsevier
Disulfiram (DSF) is currently tested in several clinical trials for cancer treatment in
combination with copper (Cu) ions. Usually, DSF and Cu are administered in two separate …

Approaches for mitigating microbial biofilm-related drug resistance: a focus on micro-and nanotechnologies

H Rao, S Choo, SR Rajeswari Mahalingam, DS Adisuri… - Molecules, 2021 - mdpi.com
Biofilms play an essential role in chronic and healthcare-associated infections and are more
resistant to antimicrobials compared to their planktonic counterparts due to their (1) …