Importance The prevalence of irritable bowel syndrome (IBS) in the United States is between
7% and 16%, most common in women and young people, with annual direct costs estimated …

Managing irritable bowel syndrome (IBS) has attracted international attention because
single-agent therapy rarely relieves bothersome symptoms for all patients. The Japanese …

Irritable bowel syndrome (IBS) is a highly prevalent, chronic disorder that significantly
reduces patients' quality of life. Advances in diagnostic testing and in therapeutic options for …

Background & Aims The existence of postinfection irritable bowel syndrome (PI-IBS) has
been substantiated by epidemiology studies conducted in diverse geographic and clinical …

The intestinal reclamation of bile acids is crucial for the maintenance of their enterohepatic
circulation. The majority of bile acids are actively absorbed via specific transport proteins …

Chronic diarrhea is a common problem affecting up to 5% of the population at a given time.
Patients vary in their definition of diarrhea, citing loose stool consistency, increased …

Irritable bowel syndrome (IBS) is associated with diverse pathophysiologic mechanisms.
These mechanisms include increased abnormal colonic motility or transit, intestinal or …

Auch wurden ähnlich wie bei der Vorgängerleitlinie die Empfehlungen zum kindlichen
Reizdarmsyndrom und Empfehlungen zur Abgrenzung intestinaler Motilitätsstörungen …

Functional gastrointestinal (GI) disorders (FGIDs) result from central and peripheral
mechanisms, cause chronic remitting-relapsing symptoms, and are associated with …

Gut microbiota and their metabolites like bile acid (BA) have been investigated as causes of
irritable bowel syndrome (IBS) symptoms. Primary BAs are synthesized and conjugated in …