Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …

The interplay between the immune and nervous systems has been acknowledged in the
past, but only more recent studies have started to unravel the cellular and molecular players …

Hematopoietic stem cells (HSC) reside in perivascular regions of the bone marrow (BM)
embedded within a complex regulatory unit called the niche. Cellular components of HSC …

Neuropeptide Y (NPY), one of the most abundant neuropeptides in the body, is widely
expressed in the central and peripheral nervous systems and acts on the cardiovascular …

Bones provide both skeletal scaffolding and space for hematopoiesis in its marrow. Previous
work has shown that these functions were tightly regulated by the nervous system. The …

Hypertension is an important risk factor for cardiovascular morbidity and mortality and for
events such as myocardial infarction, stroke, heart failure and chronic kidney disease and is …

The central nervous system regulates activity of peripheral organs through interoception. In
our previous study, we have demonstrated that PGE2/EP4 skeleton interception regulate …

Inflammation is a natural part of wound healing but it can also cause secondary (bystander)
damage and/or negatively interfere with endogenous repair mechanisms if non-resolving …

Background Acute bone loss after fracture is associated with various effects on the complete
recovery process and a risk of secondary fractures among patients. Studies have reported …

Acid sphingomyelinase (ASM) has been implicated in neurodegenerative disease
pathology, including Alzheimer's disease (AD). However, the specific role of plasma ASM in …