Unravelling exemestane: From biology to clinical prospects

AF Sobral, C Amaral, G Correia-da-Silva… - The Journal of Steroid …, 2016 - Elsevier
Aromatase inhibitors (AIs) are anti-tumor agents used in clinic to treat hormone-dependent
breast cancer. AIs block estrogens biosynthesis by inhibiting the enzyme aromatase …

Annual banned‐substance review: analytical approaches in human sports drug testing

M Thevis, T Kuuranne, H Geyer… - Drug testing and …, 2013 - Wiley Online Library
Frequently updated anti‐doping regulations and detection strategies for banned substances
and methods of doping are vital for efficient and scientifically substantiated abatement of …

Doping control analysis of 13 steroids and structural-like analytes in human urine using Quadrupole-Orbitrap LC–MS/MS with parallel reaction monitoring (PRM) …

G He, Y Wu, J Lu - Steroids, 2018 - Elsevier
Anabolic androgenic steroids (AASs) and structural-like substances are commonly
prohibited substances found in doping control studies that can be difficult to accurately …

Extraction and determination of trace amounts of three anticancer pharmaceuticals in urine by three‐phase hollow fiber liquid‐phase microextraction based on two …

A Nazaripour, Y Yamini… - Journal of separation …, 2018 - Wiley Online Library
An automated three‐phase hollow fiber liquid‐phase microextraction based on two
immiscible organic solvents followed by high‐performance liquid chromatography with UV …

Detection of designer steroid methylstenbolone in “nutritional supplement” using gas chromatography and tandem mass spectrometry: elucidation of its urinary …

G de Albuquerque Cavalcanti, FD Leal, BC Garrido… - Steroids, 2013 - Elsevier
The use of “nutritional supplements” containing unapproved substances has become a
regular practice in amateur and professional athletes. This represents a dangerous habit for …

Exemestane metabolites suppress growth of estrogen receptor-positive breast cancer cells by inducing apoptosis and autophagy: A comparative study with …

C Amaral, A Lopes, CL Varela, ET da Silva… - The international journal …, 2015 - Elsevier
Abstract Around 60–80% of all breast tumors are estrogen receptor-positive. One of the
several therapeutic approaches used for this type of cancers is the use of aromatase …

[HTML][HTML] A hydrophobic deep eutectic solvent-based vortex-assisted liquid-liquid microextraction applied for doping control of aromatase inhibitors from equine urine

Q Chen, Z Wang, H Chen - Journal of Pharmaceutical and Biomedical …, 2023 - Elsevier
Aromatase inhibitors (AIs) can indirectly cause increased testosterone in animals, which
leads to the improvement of the athletic ability of horses. For the protection of horses and the …

The Role of Metabolomics and Microbiology in Urinary Tract Infection

H Zheng, C Wang, X Yu, W Zheng, Y An… - International Journal of …, 2024 - mdpi.com
One of the common illnesses that affect women's physical and mental health is urinary tract
infection (UTI). The disappointing results of empirical anti-infective treatment and the lengthy …

A multi-technique based analytical platform for characterization and identification of a newly emerged steroid 6β-chlorotestosterone and its in-vivo epimeric …

G He, S Zhu, X Liu, J Lu, Z Wang, L Zhang, J Li - Microchemical Journal, 2024 - Elsevier
Cheating athletes tend to use new and non-approved drugs in an attempt to circumvent the
dope test. Recently, a package of unknown drug was obtained from black market claiming to …

Identification of markers of cancer in urban sewage through the use of a suspect screening approach

L Ferrando-Climent, MJ Reid… - … of Pharmaceutical and …, 2016 - Elsevier
The administration of anticancer drugs during chemotherapy treatments has increased
considerably in recent years, and based on the growing incidence of cancer worldwide there …