Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

With the acceleration of population aging, nervous system diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), Huntington's disease (HD), anxiety, depression …

Background Inulin-type fructo-oligosaccharides (FOSs) purified from Morinda officinalis
How., an effective oral antidepressant for mild to moderate depression, have a largely …

Studies reported that sodium hydrosulfide (NaHS) can remit the depressive-like and anxiety-
like behaviors induced by type 1 diabetes mellitus (T1DM). However, the mechanism is still …

Injuries of the central (CNS) and peripheral nervous system (PNS) are a serious problem of
the modern healthcare system. The situation is complicated by the lack of clinically effective …

Increasing evidence confirms that sleep deprivation (SD), which induces hippocampal
neuroinflammation, is a risk factor for depression. Hydrogen sulfide (H 2 S) is a novel …

Background & Objective: Hydrogen sulfide [H2S] has been widely known as a toxic gas for
more than 300 years in the scientific community. However, the understanding about this …

Significance: Redox pioneer Helmut Sies attempted to explain reactive species' challenges
faced by organelles, cells, tissues, and organs via three complementary definitions:(i) …

Depression is highly prevalent in individuals with diabetes, and depressive symptoms are
less responsive to current antidepressant therapies. Oxidative stress plays a major role both …

Chronic unpredictable mild stress (CUMS) induces hippocampal oxidative stress. H2S
functions as a neuroprotectant against oxidative stress in brain. We have previously shown …