Aminolevulinate dehydratase (δ-ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations

JBT Rocha, RA Saraiva, SC Garcia… - Toxicology …, 2012 - academic.oup.com
Abstract δ-ALA-D is a metalloenzyme that has 3 vicinal thiol/thiolate groups that coordinate
with Zn (ii). The proximity between the sulfhydryl groups renders δ-ALA-D extremely …

Evaluation of pesticide-induced oxidative stress from a gene–environment interaction perspective

AF Hernández, M Lacasaña, F Gil… - Toxicology, 2013 - Elsevier
Previously we reported that intensive agriculture workers exposed to pesticides had
decreased levels of the intraerythrocyte enzymes delta-9-aminolevulinic acid dehydratase …

In vivo assessment of dichlorvos induced histological and biochemical impairments coupled with expression of p53 responsive apoptotic genes in the liver and kidney …

SP Trivedi, A Ratn, Y Awasthi, M Kumar… - … and Physiology Part C …, 2021 - Elsevier
Sub-lethal exposure of dichlorvos induces oxidative stress, consequent genetic instability
and apoptosis coupled with impairments in biochemical, histopathological and transcription …

Temporal expression profiling of plasma proteins reveals oxidative stress in early stages of Type 1 Diabetes progression

CW Liu, L Bramer, BJ Webb-Robertson, K Waugh… - Journal of …, 2018 - Elsevier
Blood markers other than islet autoantibodies are greatly needed to indicate the pancreatic
beta cell destruction process as early as possible, and more accurately reflect the …

[HTML][HTML] Rapamycin increases oxidative stress response gene expression in adult stem cells

AE Kofman, MR McGraw, CJ Payne - Aging (Albany NY), 2012 - ncbi.nlm.nih.gov
Balancing quiescence with proliferation is of paramount importance for adult stem cells in
order to avoid hyperproliferation and cell depletion. In some models, stem cell exhaustion …

Association between blood lead levels and delta-aminolevulinic acid dehydratase in pregnant women

O La-Llave-León, EM Méndez-Hernández… - International journal of …, 2017 - mdpi.com
Blood lead levels (BLLs) and delta-aminolevulinic acid dehydratase (ALAD) activity are
considered biomarkers of lead exposure and lead toxicity, respectively. The present study …

Pre-Ride Biomarkers and Endurance Horse Welfare: Analyzing the Impact of the Elimination of Superoxide Dismutase, δ-Aminolevulinic-Dehydratase, Thiobarbituric …

L Bollinger, A Bartel, C Weber, H Gehlen - Animals, 2023 - mdpi.com
Simple Summary Endurance riding is a physiologically highly demanding equestrian sport
for riders and athletes. The sport has strict vet controls; depending on the distance, between …

Quercetin prevents alterations of behavioral parameters, delta‐aminolevulinic dehydratase activity, and oxidative damage in brain of rats in a prenatal model of autism

BS de Mattos, MSP Soares, L Spohr… - International Journal …, 2020 - Wiley Online Library
Autism is a neuropathology characterized by behavioral disorders. Considering that
oxidative stress is involved in the pathophysiology of this disease, we evaluated the effects …

Delta-aminolevulinate dehydratase activity and oxidative stress markers in preeclampsia

L de Lucca, F Rodrigues, LB Jantsch, H Kober… - Biomedicine & …, 2016 - Elsevier
Preeclampsia is an important pregnancy-specific multisystem disorder characterized by the
onset of hypertension and proteinuria. It is of unknown etiology and involves serious risks for …

Mutagenic, genotoxic and enzyme inhibitory effects of carbosulfan in rainbow trout Oncorhynchus mykiss

I Altinok, E Capkin, H Boran - Pesticide biochemistry and physiology, 2012 - Elsevier
Rainbow trout (Oncorhynchus mykiss; 116.88±21.69 g) were exposed to sublethal
concentrations (25μg/L) of carbosulfan for 60days to test if the long term exposure of fish to …