The neurotrophic factor BDNF is an important regulator for the development of brain circuits,
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …

Dysregulation of the immune system in endometriotic milieus has been considered to play a
pivotal role in the pathogenesis of endometriosis. Macrophage recruitment and nerve fiber …

Background Glioblastoma multiforme (GBM) is the most common cancer of the central
nervous system, while Parkinson's disease (PD) is a degenerative neurological condition …

Glioblastoma is the most lethal primary brain tumor; however, the crosstalk between
glioblastoma stem cells (GSCs) and their supportive niche is not well understood. Here, we …

Background: Head and neck squamous cell carcinoma (HNSCC) is the seventh most
common type of cancer worldwide. Its highly aggressive and heterogeneous nature and …

Enhancement of brain-derived neurotrophic factor (BDNF) signalling has great potential in
therapy for neurological and psychiatric disorders. This neurotrophin not only attenuates cell …

Neurotrophins (NTs) as nerve growth factor (NGF) and brain-derived neurotrophic factor
(BDNF) play multiple roles in different settings including neuronal development, function and …

Receptor tyrosine kinases (RTKs) play important roles in cell growth, motility, differentiation,
and survival. These single-pass membrane proteins are grouped into subfamilies based on …

Recent studies have demonstrated a critical role for nerves in enabling tumor progression.
The association of nerves with cancer cells is well established for a variety of malignant …

Ischemic stroke is a major cause of mortality and disability worldwide. As a part of Traditional
Chinese Medicine (TCM), acupuncture has been shown to be effective in promoting …