[HTML][HTML] MicroRNA-122 mimic/microRNA-221 inhibitor combination as a novel therapeutic tool against hepatocellular carcinoma

M Hassan, M Elzallat, T Aboushousha… - Non-coding RNA …, 2023 - Elsevier
Abstract Background Therapeutic microRNAs (miRNAs) delivery holds a lot of promise for
treating human malignancies. So, this study was carried out to examine the potential of miR …

[HTML][HTML] Nanoconjugated long non-coding RNA MEG3 as a new therapeutic approach for Hepatocellular carcinoma

M Elzallat, M Hassan, N Elkramani, T Aboushousha… - Heliyon, 2023 - cell.com
Background Hepatocellular carcinoma (HCC) is an aggressive human cancer with a poor
prognosis. Long non-coding RNAs (lncRNA) have multiple functions: epigenomic regulation …

NAC1 transcriptional activation of LDHA induces hepatitis B virus immune evasion leading to cirrhosis and hepatocellular carcinoma development

W Chen, L Guo, H Xu, Y Dai, J Yao, L Wang - Oncogenesis, 2024 - nature.com
Our study aimed to elucidate the molecular mechanisms underlying NAC1 (nucleus
accumbens associated 1) transcriptional regulation of LDHA and its role in HBV immune …

Innovative model of surface-enhanced Raman spectroscopy for exosomes identification: An approach for the diagnosis of hepatocellular carcinoma

A Elkady, M Hassan, MF Hagag, E El-Ahwany… - Clinica chimica acta, 2023 - Elsevier
Background The current hepatocellular carcinoma (HCC) diagnostic approaches lack
adequate sensitivity and specificity. So, this study was performed to develop an innovative …