Recent advances in the synthesis of sialic acid derivatives and sialylmimetics as biological probes

MJ Kiefel, M von Itzstein - Chemical reviews, 2002 - ACS Publications
There has been intense interest during recent years in identifying the biological functions of
carbohydrates. This diverse class of biomolecule is now well recognized as playing …

Thiooligosaccharides in glycobiology

H Driguez - Glycoscience Synthesis of Substrate Analogs and …, 2008 - Springer
The chemical syntheses of thiooligosaccharides which were reported up to the beginning of
1996 are reviewed. Therefore, this article brings up to date previous reviews on …

Chemistry, biochemistry and biology of sialic acids

R Schauer, JP Kamerling - New comprehensive biochemistry, 1997 - Elsevier
Since the discovery of N-acetylneuraminic acid, the most universal sialic acid, at the end of
the 1930s [1],[2] as well as the structural and stereochemical elucidation of its free and …

Glyconanoparticles for the plasmonic detection and discrimination between human and avian influenza virus

MJ Marín, A Rashid, M Rejzek, SA Fairhurst… - Organic & …, 2013 - pubs.rsc.org
A plasmonic bioassay for the specific detection of human influenza virus has been
developed based on gold nanoparticles functionalised with a designed and synthesised …

Chemical synthesis and medicinal applications of glycoporphyrins

C Moylan, EM Scanlan… - Current Medicinal …, 2015 - ingentaconnect.com
This review presents an in-depth overview of the modification of porphyrins with
bioconjugates and their applications in medicine today. Porphyrin bioconjugates ranging …

Second generation of thiazolylmannosides, FimH antagonists for E. coli-induced Crohn's disease

T Chalopin, DA Dorta, A Sivignon, M Caudan… - Organic & …, 2016 - pubs.rsc.org
The anti-adhesive strategy, consisting of disrupting bacterial attachment to the host cells, is
widely explored as an alternative to antibiotic therapies. Recently, thiazolylmannosides …

S-Linked Ganglioside Analogues for Use in Conjugate Vaccines

JR Rich, DR Bundle - Organic Letters, 2004 - ACS Publications
Glycosidase resistant thioglycoside precursors of the melanoma-associated ganglioside
GM2 have been synthesized starting from lactose. Syntheses of several analogues of …

Non-conventional glycosidic linkages: Syntheses and structures of thiooligosaccharides and carbohydrates with three-bond glycosidic connections

L Szilagyi, O Varela - Current Organic Chemistry, 2006 - ingentaconnect.com
Thiooligosaccharides display inhibitory activity against glycoside hydrolases and they
constitute a valuable tool for structural biology. The construction of the interglycosidic …

Investigation of the stability of thiosialosides toward hydrolysis by sialidases using NMR spectroscopy

JC Wilson, MJ Kiefel, DI Angus, M Von Itzstein - Organic letters, 1999 - ACS Publications
1H NMR spectroscopy has been used to investigate whether the α (2→ 6)-linked
thiosialoside 3 and the α (2→ 3)-linked thiosialoside 9 are hydrolyzed in the presence of …

Synthesis and Biological Evaluation of N-Acetylneuraminic Acid-Based Rotavirus Inhibitors

MJ Kiefel, B Beisner, S Bennett, ID Holmes… - Journal of medicinal …, 1996 - ACS Publications
Rotavirus can cause severe gastrointestinal disease, especially in infants and young
children, and is particularly prevalent in Third-World countries. Therefore, the development …