Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

An important motivation for the use of nanomaterials and nanoarchitectures in cancer
therapy emanates from the widespread emergence of drug resistance. Although doxorubicin …

The scarcity of novel and effective therapeutics for the treatment of cancer is a pressing and
alarming issue that needs to be prioritized. The number of cancer cases and deaths are …

Breast cancer (BC) is the most prevalent malignant neoplasm among women and is the fifth
most common cause of cancer-associated death worldwide. Acquired chemoresistance …

In recent years, with the development of nanomaterials, the research of drug delivery
systems has become a new field of cancer therapy. Compared with conventional antitumor …

The success of targeted drug therapy for cancer patients has attracted extensive attention
from academia and society. However, the rapid development of acquired drug resistance is …

Drug conjugates have become a significant focus of research in the field of targeted
medicine for cancer treatments. Peptide-drug conjugates (PDCs), a subset of drug …

Simple Summary Accumulating evidence indicates that hypoxia-inducible factor-1 (HIF-1)
plays a pivotal role in tumor biology, particularly in hypoxic environments. Over the past few …

Simple Summary Organometallics, such as copper compounds, are cancer
chemotherapeutics used alone or in combination with other drugs. One small group of …

Tissue hypoxia in solid tumors is caused by several pathological changes associated with
tumor growth, including altered microvasculature structure, increased diffusional distances …