Updating the striatal–pallidal wiring diagram

LZ Fang, MC Creed - Nature neuroscience, 2024 - nature.com
The striatal and pallidal complexes are basal ganglia structures that orchestrate learning
and execution of flexible behavior. Models of how the basal ganglia subserve these …

The nucleus accumbens in reward and aversion processing: insights and implications

Y Xu, Y Lin, M Yu, K Zhou - Frontiers in Behavioral Neuroscience, 2024 - frontiersin.org
The nucleus accumbens (NAc), a central component of the brain's reward circuitry, has been
implicated in a wide range of behaviors and emotional states. Emerging evidence, primarily …

CCK+ Interneurons Contribute to Thalamus-Evoked Feed-Forward Inhibition in the Prelimbic Prefrontal Cortex

A Kamalova, K Manoocheri, X Liu… - Journal of …, 2024 - Soc Neuroscience
Interneurons in the medial prefrontal cortex (PFC) regulate local neural activity to influence
cognitive, motivated, and emotional behaviors. Parvalbumin-expressing (PV+) interneurons …

Sex-specific GABAergic microcircuits that switch vulnerability into resilience to stress and reverse the effects of chronic stress exposure

T Jiang, M Feng, A Hutsell, B Lüscher - Molecular Psychiatry, 2024 - nature.com
Clinical and preclinical studies have identified somatostatin (SST)-positive interneurons as
critical elements that regulate the vulnerability to stress-related psychiatric disorders …

Dissociable encoding of motivated behavior by parallel thalamo-striatal projections

S Beas, I Khan, C Gao, G Loewinger, E Macdonald… - Current Biology, 2024 - cell.com
The successful pursuit of goals requires the coordinated execution and termination of
actions that lead to positive outcomes. This process relies on motivational states that are …

Ventral subiculum inputs to nucleus accumbens medial shell preferentially innervate D2R medium spiny neurons and contain calcium permeable AMPARs

EE Boxer, JM Kim, B Dunn, J Aoto - Journal of Neuroscience, 2023 - Soc Neuroscience
Ventral subiculum (vSUB) is the major output region of ventral hippocampus (vHIPP) and
sends major projections to nucleus accumbens medial shell (NAcMS). Hyperactivity of the …

Sex-specific GABAergic microcircuits that switch vulnerability into resilience to stress and reverse the effects of chronic stress exposure

B Luscher, T Jiang, M Feng, A Hutsell - Research Square, 2024 - pmc.ncbi.nlm.nih.gov
Clinical and preclinical studies have identified somatostatin (SST)-positive interneurons as
key elements that regulate the vulnerability to stress-related psychiatric disorders …

Characterizing Ventral Subiculum to Nucleus Accumbens Medial Shell Synapses and the Role of Neurexin-3

JM Kim - 2024 - search.proquest.com
The nucleus accumbens (NAc) and its afferents are critical for processing reward-related
information in the brain. While it is known that the ventral hippocampus (vHIPP) sends the …

Structural, Functional, and Behavioral Outcomes of Stimulus-Dependent Transcription in Nucleus Accumbens Parvalbumin-Expressing Interneurons

MF Hazlett - 2022 - search.proquest.com
Learning and memory are mediated by changes in synaptic and neuronal function within
brain circuits, and is supported by dynamic waves of stimulus-dependent transcription in the …