A promising cell-therapy approach for heart failure aims at differentiating human pluripotent
stem cells (hPSCs) into functional cardiomyocytes (CMs) in vitro to replace the disease …

Metabolic switches are a crucial hallmark of cellular development and regeneration. In
response to changes in their environment or physiological state, cells undergo coordinated …

Introduction Premature infants (PIs) are at risk of suffering necrotizing enterocolitis (NEC),
and infants consuming human milk (HM) show a lower incidence than infants receiving …

The limited endogenous regenerative capacity of the human heart renders cardiovascular
diseases a major health threat, thus motivating intense research on in vitro heart cell …

The heart undergoes a dynamic maturation process following birth, in response to a wide
range of stimuli, including both physiological and pathological cues. This process entails …

The gut microbiome is widely recognized as a dynamic organ with a profound influence on
human physiology and pathology. Extensive epidemiological and longitudinal cohort studies …

TAZ is an acyltransferase essential for remodeling and maturation of cardiolipin, a signature
phospholipid of mitochondria. Nascent cardiolipin contains a mixture of fatty acyl chains …

The heart, once considered a mere blood pump, is now recognized as a multifunctional
metabolic and endocrine organ. Its function is tightly regulated by various metabolic …

Breastfeeding is an important determinant of infant health and there is immense interest in
understanding its metabolite composition so that key beneficial components can be …

Long chain fatty acids in the colon play important roles in infant development. This study
aimed to establish a colon-targeted long chain fatty acid release system in rat pups, with …