De novo design of high-affinity protein binders with AlphaProteo
V Zambaldi, D La, AE Chu, H Patani… - arXiv preprint arXiv …, 2024 - arxiv.org
Computational design of protein-binding proteins is a fundamental capability with broad
utility in biomedical research and biotechnology. Recent methods have made strides against …
utility in biomedical research and biotechnology. Recent methods have made strides against …
[HTML][HTML] Short circuit: Transcription factor addiction as a growing vulnerability in cancer
Core regulatory circuitry refers to the network of lineage-specific transcription factors
regulating expression of both their own coding genes, and that of other transcription factors …
regulating expression of both their own coding genes, and that of other transcription factors …