Genotyping and interpretation of STR-DNA: low-template, mixtures and database matches—twenty years of research and development

P Gill, H Haned, O Bleka, O Hansson, G Dørum… - Forensic Science …, 2015 - Elsevier
Abstract The introduction of Short Tandem Repeat (STR) DNA was a revolution within a
revolution that transformed forensic DNA profiling into a tool that could be used, for the first …

EuroForMix: An open source software based on a continuous model to evaluate STR DNA profiles from a mixture of contributors with artefacts

Ø Bleka, G Storvik, P Gill - Forensic Science International: Genetics, 2016 - Elsevier
We have released a software named EuroForMix to analyze STR DNA profiles in a user-
friendly graphical user interface. The software implements a model to explain the allelic …

[图书][B] Forensic biology: identification and DNA analysis of biological evidence

R Li - 2008 - taylorfrancis.com
Designed as an accessible introduction to basic scientific principles and their application in
professional practice, Forensic Biology provides a concise overview of the field. Focusing …

Analysis of forensic DNA mixtures with artefacts

RG Cowell, T Graversen, SL Lauritzen… - Journal of the Royal …, 2015 - academic.oup.com
DNA is now routinely used in criminal investigations and court cases, although DNA
samples taken at crime scenes are of varying quality and therefore present challenging …

Validating TrueAllele® Interpretation of DNA Mixtures Containing up to Ten Unknown Contributors

DW Bauer, N Butt, JM Hornyak… - Journal of forensic …, 2020 - Wiley Online Library
Most DNA evidence is a mixture of two or more people. Cybergenetics TrueAllele® system
uses Bayesian computing to separate genotypes from mixture data and compare genotypes …

TrueAllele® Genotype Identification on DNA Mixtures Containing up to Five Unknown Contributors

MW Perlin, JM Hornyak, G Sugimoto… - Journal of forensic …, 2015 - Wiley Online Library
Computer methods have been developed for mathematically interpreting mixed and low‐
template DNA. The genotype modeling approach computationally separates out the …

TrueAllele casework on Virginia DNA mixture evidence: computer and manual interpretation in 72 reported criminal cases

MW Perlin, K Dormer, J Hornyak… - PLoS …, 2014 - journals.plos.org
Mixtures are a commonly encountered form of biological evidence that contain DNA from
two or more contributors. Laboratory analysis of mixtures produces data signals that usually …

Single nucleotide polymorphism

C Børsting, V Pereira, JD Andersen… - A Guide to Forensic …, 2016 - books.google.com
Genetic variations in specific base pair positions in the genome (Figure 1) are called single
nucleotide polymorphisms (SNPs) if at least two variants (alleles) have frequencies of more …

Probabilistic characterisation of baseline noise in STR profiles

UJ Mönich, K Duffy, M Médard, V Cadambe… - Forensic Science …, 2015 - Elsevier
There are three dominant contributing factors that distort short tandem repeat profile
measurements, two of which, stutter and variations in the allelic peak heights, have been …

LoCIM-tool: an expert's assistant for inferring the major contributor's alleles in mixed consensus DNA profiles

CCG Benschop, T Sijen - Forensic Science International: Genetics, 2014 - Elsevier
When dealing with mixed DNA profiles where contributors have donated DNA in unequal
amounts, it is often useful to deduce the genotype of the major contributor. Inference of a …