Genotyping and interpretation of STR-DNA: low-template, mixtures and database matches—twenty years of research and development
Abstract The introduction of Short Tandem Repeat (STR) DNA was a revolution within a
revolution that transformed forensic DNA profiling into a tool that could be used, for the first …
revolution that transformed forensic DNA profiling into a tool that could be used, for the first …
EuroForMix: An open source software based on a continuous model to evaluate STR DNA profiles from a mixture of contributors with artefacts
We have released a software named EuroForMix to analyze STR DNA profiles in a user-
friendly graphical user interface. The software implements a model to explain the allelic …
friendly graphical user interface. The software implements a model to explain the allelic …
[图书][B] Forensic biology: identification and DNA analysis of biological evidence
R Li - 2008 - taylorfrancis.com
Designed as an accessible introduction to basic scientific principles and their application in
professional practice, Forensic Biology provides a concise overview of the field. Focusing …
professional practice, Forensic Biology provides a concise overview of the field. Focusing …
Analysis of forensic DNA mixtures with artefacts
RG Cowell, T Graversen, SL Lauritzen… - Journal of the Royal …, 2015 - academic.oup.com
DNA is now routinely used in criminal investigations and court cases, although DNA
samples taken at crime scenes are of varying quality and therefore present challenging …
samples taken at crime scenes are of varying quality and therefore present challenging …
Validating TrueAllele® Interpretation of DNA Mixtures Containing up to Ten Unknown Contributors
DW Bauer, N Butt, JM Hornyak… - Journal of forensic …, 2020 - Wiley Online Library
Most DNA evidence is a mixture of two or more people. Cybergenetics TrueAllele® system
uses Bayesian computing to separate genotypes from mixture data and compare genotypes …
uses Bayesian computing to separate genotypes from mixture data and compare genotypes …
TrueAllele® Genotype Identification on DNA Mixtures Containing up to Five Unknown Contributors
MW Perlin, JM Hornyak, G Sugimoto… - Journal of forensic …, 2015 - Wiley Online Library
Computer methods have been developed for mathematically interpreting mixed and low‐
template DNA. The genotype modeling approach computationally separates out the …
template DNA. The genotype modeling approach computationally separates out the …
TrueAllele casework on Virginia DNA mixture evidence: computer and manual interpretation in 72 reported criminal cases
MW Perlin, K Dormer, J Hornyak… - PLoS …, 2014 - journals.plos.org
Mixtures are a commonly encountered form of biological evidence that contain DNA from
two or more contributors. Laboratory analysis of mixtures produces data signals that usually …
two or more contributors. Laboratory analysis of mixtures produces data signals that usually …
Single nucleotide polymorphism
C Børsting, V Pereira, JD Andersen… - A Guide to Forensic …, 2016 - books.google.com
Genetic variations in specific base pair positions in the genome (Figure 1) are called single
nucleotide polymorphisms (SNPs) if at least two variants (alleles) have frequencies of more …
nucleotide polymorphisms (SNPs) if at least two variants (alleles) have frequencies of more …
Probabilistic characterisation of baseline noise in STR profiles
There are three dominant contributing factors that distort short tandem repeat profile
measurements, two of which, stutter and variations in the allelic peak heights, have been …
measurements, two of which, stutter and variations in the allelic peak heights, have been …
LoCIM-tool: an expert's assistant for inferring the major contributor's alleles in mixed consensus DNA profiles
CCG Benschop, T Sijen - Forensic Science International: Genetics, 2014 - Elsevier
When dealing with mixed DNA profiles where contributors have donated DNA in unequal
amounts, it is often useful to deduce the genotype of the major contributor. Inference of a …
amounts, it is often useful to deduce the genotype of the major contributor. Inference of a …