Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Z Celebi Sozener, B Ozdel Ozturk, P Cerci, M Turk… - Allergy, 2022 - Wiley Online Library
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Allergic rhinitis and its impact on asthma (ARIA) 2008

J Bousquet, N Khaltaev, AA Cruz, J Denburg… - Allergy, 2008 - Wiley Online Library
Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

Changing trends in asthma prevalence among children

LJ Akinbami, AE Simon, LM Rossen - Pediatrics, 2016 - publications.aap.org
BACKGROUND: Childhood asthma prevalence doubled from 1980 to 1995 and then
increased more slowly from 2001 to 2010. During this second period, racial disparities …

The microbiome in asthma

YJ Huang, HA Boushey - Journal of Allergy and Clinical Immunology, 2015 - Elsevier
The application of recently developed sensitive, specific, culture-independent tools for
identification of microbes is transforming concepts of microbial ecology, including concepts …

A systematic review of socioeconomic position in relation to asthma and allergic diseases

E Uphoff, B Cabieses, M Pinart… - European …, 2015 - Eur Respiratory Soc
The role of socioeconomic position (SEP) in the development of asthma and allergies is
unclear, with some pointing to the risks of low SEP and other research pointing in the …

Flavonoids and related compounds as anti-allergic substances

M Kawai, T Hirano, S Higa, J Arimitsu, M Maruta… - Allergology …, 2007 - Elsevier
The prevalence of allergic diseases has increased all over the world during the last two
decades. Dietary change is considered to be one of the environmental factors that cause this …

Too clean, or not too clean: the hygiene hypothesis and home hygiene

SF Bloomfield, R Stanwell‐Smith… - Clinical & …, 2006 - Wiley Online Library
The 'hygiene hypothesis' as originally formulated by Strachan, proposes that a cause of the
recent rapid rise in atopic disorders could be a lower incidence of infection in early …

The association between phthalates in dust and allergic diseases among Bulgarian children

B Kolarik, K Naydenov, M Larsson… - Environmental …, 2008 - ehp.niehs.nih.gov
Background Recent studies have identified associations between the concentration of
phthalates in indoor dust and allergic symptoms in the airways, nose, and skin. Objectives …

[HTML][HTML] The role of PPAR-γ in allergic disease

JM Stark, JM Coquet, CA Tibbitt - Current Allergy and Asthma Reports, 2021 - Springer
Abstract Purpose of Review The incidence of allergic diseases such as asthma, rhinitis and
atopic dermatitis has risen at an alarming rate over the last century. Thus, there is a clear …

The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance?

LG Hersoug, A Linneberg - Allergy, 2007 - Wiley Online Library
There is increasing epidemiological evidence that obesity increases the risk of asthma,
atopic, and autoimmune diseases. We hypothesize that the increase in these diseases is …