Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance
C Liao, X Huang, Q Wang, D Yao, W Lu - Frontiers in cellular and …, 2022 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections in
severely ill and immunocompromised patients. Ubiquitously disseminated in the …
severely ill and immunocompromised patients. Ubiquitously disseminated in the …
Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets
V Kumar - International immunopharmacology, 2020 - Elsevier
Cytokine storm generates during various systemic acute infections, including sepsis and
current pandemic called COVID-19 (severe) causing devastating inflammatory conditions …
current pandemic called COVID-19 (severe) causing devastating inflammatory conditions …
Toll-like receptors in the pathogenesis of neuroinflammation
V Kumar - Journal of Neuroimmunology, 2019 - Elsevier
Toll-like receptors (TLRs) are discovered as crucial pattern recognition receptors (PRRs)
involved in the recognition of pathogen-associated molecular patterns (PAMPs). Later …
involved in the recognition of pathogen-associated molecular patterns (PAMPs). Later …
Recent clinical trends in Toll‐like receptor targeting therapeutics
Toll‐like receptors (TLRs) are germline‐encoded receptors that are central to innate and
adaptive immune responses. Owing to their vital role in inflammation, TLRs are rational …
adaptive immune responses. Owing to their vital role in inflammation, TLRs are rational …
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
T Kawai, S Akira - Immunity, 2011 - cell.com
Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that
play a central role in host cell recognition and responses to microbial pathogens. TLR …
play a central role in host cell recognition and responses to microbial pathogens. TLR …
Sertoli cell immune regulation: a double-edged sword
The testis must create and maintain an immune privileged environment to protect maturing
germ cells from autoimmune destruction. The establishment of this protective environment is …
germ cells from autoimmune destruction. The establishment of this protective environment is …
Acute lower respiratory tract infection
JP Mizgerd - New England Journal of Medicine, 2008 - Mass Medical Soc
Acute lower respiratory tract infections are a major cause of death and disability, yet the
mechanisms that make such infections so virulent are not entirely understood. This review …
mechanisms that make such infections so virulent are not entirely understood. This review …
Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract
MC Lane, CJ Alteri, SN Smith… - Proceedings of the …, 2007 - National Acad Sciences
Uropathogenic Escherichia coli (UPEC) cause most uncomplicated urinary tract infections
(UTIs) in humans. Because UTIs are considered to occur in an ascending manner, flagellum …
(UTIs) in humans. Because UTIs are considered to occur in an ascending manner, flagellum …
Innate immune recognition in infectious and noninfectious diseases of the lung
B Opitz, V van Laak, J Eitel, N Suttorp - American journal of …, 2010 - atsjournals.org
Diseases of the respiratory tract are among the leading causes of death in the world
population. Increasing evidence points to a key role of the innate immune system with its …
population. Increasing evidence points to a key role of the innate immune system with its …
[HTML][HTML] Deletion of TLR5 results in spontaneous colitis in mice
M Vijay-Kumar, CJ Sanders, RT Taylor… - The Journal of …, 2007 - Am Soc Clin Investig
Activation of TLRs by bacterial products results in rapid activation of genes encoding
products designed to protect the host from perturbing microbes. In the intestine, which is …
products designed to protect the host from perturbing microbes. In the intestine, which is …