Infrared spectroscopy has played an instrumental role in the study of a wide variety of
biological questions. However, in many cases, it is impossible or difficult to rely on the …

We review a theory for coupled many-nonlinear oscillator systems that describes quantum
ergodicity and energy flow in molecules. The theory exploits the isomorphism between …

The advent of laser-based sources of ultrafast infrared pulses has extended the study of very
fast molecular dynamics to the observation of processes manifested through their effects on …

Amyloid diseases, including neurodegenerative diseases such as Alzheimer's and
Parkinson's, are linked to a poorly understood progression of protein misfolding and …

Energy transport in molecules is essential for many areas of science and technology. Strong
covalent bonds of a molecular backbone can facilitate the involvement of the molecule's …

This review presents an overview of the relaxation-assisted two-dimensional infrared (RA
2DIR) spectroscopy method for measuring structures and energy transport dynamics in …

We explore the capability of the azidohomoalanine (Aha) as a vibrational label for 2D IR
spectroscopy to study the binding of the target peptide to the PDZ2 domain. The Aha label …

An approach is presented to calculate thermal boundary resistance in molecules, which
occurs, for example, at the interfaces between moieties held at fixed temperatures and a …

Energy transport during chemical reactions or following photoexcitation in systems of
biological molecules is mediated by numerous interfaces that separate chemical groups and …

The coupling between different vibrational modes in proteins is essential for chemical
dynamics and biological functions and is linked to the propagation of conformational …