Ras homolog gene family member A (RhoA) is a small GTPase of the Rho family involved in
regulating multiple signal transduction pathways that influence a diverse range of cellular …

Methylmercury (MeHg) is a widely known environmental pollutant that causes severe
neurotoxicity. MeHg-induced neurotoxicity depends on various cellular conditions, including …

Triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane protein that
is predominantly expressed by microglia in the brain. The proteolytic shedding of TREM2 …

Precise timing of macrophage polarization plays a pivotal role in immunomodulation of
tissue regeneration, yet most studies mainly focus on M2 macrophages for their anti …

Epithelial-mesenchymal transition (EMT) refers to the conversion of epithelial cells to
mesenchymal phenotype, which endows the epithelial cells with enhanced migration …

Neurotrophins constitute a family of growth factors initially characterized as predominant
mediators of nervous system development, neuronal survival, regeneration and plasticity …

Increasing evidence suggests that in vitro fertilization (IVF) may be associated with an
increased risk of developing obesity and metabolic diseases later in life in the offspring …

Background Multiple sclerosis (MS) is one of the most common neurological diseases that
cause chronic inflammation of the central nervous system and demyelination of the myelin …

Chronic obstructive pulmonary disease (COPD) is a chronic disease associated with
inflammation and structural changes in the airways and lungs, resulting from a combination …

Scrapie infection, which converts cellular prion protein (PrPC) into the pathological and
infectious isoform (PrPSc), leads to neuronal cell death, glial cell activation and PrPSc …