Simple Summary Intercellular adhesion molecule 1 (ICAM-1) is a protein produced by cells
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …

The influence of host genetics on susceptibility to Plasmodium falciparum malaria has been
extensively studied over the past twenty years. It is now clear that malaria parasites have …

Home to a culturally heterogeneous population, India is also a melting pot of genetic
diversity. The population architecture characterized by multiple endogamous groups with …

The past 10 years have generated new insights into the complex interaction between CD36
(cluster of differentiation 36) and malaria. These range from the crystallization of the CD36 …

Populations exposed to Plasmodium infection develop genetic mechanisms of protection
against severe disease. The clinical manifestation of malaria results primarily from the lysis …

APOBEC3B, a gene involved in innate response, exhibits insertion–deletion polymorphism
across world populations. We observed the insertion allele to be nearly fixed in malaria …

Abstract The Indian Genome Variation Consortium (IGVC) project, an initiative of the Council
for Scientific and Industrial Research, has been the first large-scale comprehensive study of …

There have been concerted efforts toward cataloging rare and deleterious variants in
different world populations using high‐throughput genotyping and sequencing‐based …

Background With over 1.3 billion people, India is estimated to contain three times more
genetic diversity than does Europe. Next-generation sequencing technologies have …

The genetic basis for susceptibility to malaria has been studied widely in African populations
but less is known of the contribution of specific genetic variants in Asian populations. We …