Role of animal models in biomedical research: a review
The animal model deals with the species other than the human, as it can imitate the disease
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …
Regenerative capacity of adipose derived stem cells (ADSCs), comparison with mesenchymal stem cells (MSCs)
L Mazini, L Rochette, M Amine, G Malka - International journal of …, 2019 - mdpi.com
Adipose tissue is now on the top one of stem cell sources regarding its accessibility,
abundance, and less painful collection procedure when compared to other sources. The …
abundance, and less painful collection procedure when compared to other sources. The …
[HTML][HTML] Mesenchymal stem cell related therapies for cartilage lesions and osteoarthritis
R Zhang, J Ma, J Han, W Zhang… - American journal of …, 2019 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a common degenerative joint disease characterized by cartilage
degradation, synovitis, subchondral bone sclerosis and osteophyte formation. Current …
degradation, synovitis, subchondral bone sclerosis and osteophyte formation. Current …
Articular cartilage: from formation to tissue engineering
S Camarero-Espinosa, B Rothen-Rutishauser… - Biomaterials …, 2016 - pubs.rsc.org
Hyaline cartilage is the nonlinear, inhomogeneous, anisotropic, poro-viscoelastic connective
tissue that serves as friction-reducing and load-bearing cushion in synovial joints and is vital …
tissue that serves as friction-reducing and load-bearing cushion in synovial joints and is vital …
Mechanical versus enzymatic isolation of stromal vascular fraction cells from adipose tissue
JA Aronowitz, RA Lockhart, CS Hakakian - Springerplus, 2015 - Springer
Clinical use of adipose-derived stem cells (ASCs) for a variety of indications is rapidly
expanding in medicine. Most commonly, ASCs are isolated at the point of care from …
expanding in medicine. Most commonly, ASCs are isolated at the point of care from …
Pathophysiological perspective of osteoarthritis
Osteoarthritis (OA) is the most well-known degenerative disease among the geriatric and is
a main cause of significant disability in daily living. It has a multifactorial etiology and is …
a main cause of significant disability in daily living. It has a multifactorial etiology and is …
Recent developed strategies for enhancing Chondrogenic differentiation of MSC: impact on MSC‐based therapy for cartilage regeneration
K Zha, Z Sun, Y Yang, M Chen, C Gao… - Stem Cells …, 2021 - Wiley Online Library
Articular cartilage is susceptible to damage, but its self‐repair is hindered by its avascular
nature. Traditional treatment methods are not able to achieve satisfactory repair effects, and …
nature. Traditional treatment methods are not able to achieve satisfactory repair effects, and …
Two-year clinical outcomes of autologous microfragmented adipose tissue in elderly patients with knee osteoarthritis: a multi-centric, international study
Purpose The aim of this study is to evaluate the outcomes of autologous microfragmented
adipose tissue (MFAT) injection in elderly patients with knee osteoarthritis (OA). We …
adipose tissue (MFAT) injection in elderly patients with knee osteoarthritis (OA). We …
Adipose‐derived mesenchymal stem cells for the treatment of articular cartilage: a systematic review on preclinical and clinical evidence
F Perdisa, N Gostyńska, A Roffi, G Filardo… - Stem cells …, 2015 - Wiley Online Library
Among the current therapeutic approaches for the regeneration of damaged articular
cartilage, none has yet proven to offer results comparable to those of native hyaline …
cartilage, none has yet proven to offer results comparable to those of native hyaline …
The effect of intra‐articular injection of autologous bone marrow stem cells on pain and knee function in patients with osteoarthritis
D Garay‐Mendoza, L Villarreal‐Martínez… - … journal of rheumatic …, 2018 - Wiley Online Library
Aim Management of osteoarthritis (OA) is basically symptomatic. Recently, stem cells (SC)
have been used in the search for an optimum treatment. We decided to conduct a controlled …
have been used in the search for an optimum treatment. We decided to conduct a controlled …