Encapsulins

TW Giessen - Annual review of biochemistry, 2022 - annualreviews.org
Subcellular compartmentalization is a defining feature of all cells. In prokaryotes,
compartmentalization is generally achieved via protein-based strategies. The two main …

Advances in encapsulin nanocompartment biology and engineering

JA Jones, TW Giessen - Biotechnology and bioengineering, 2021 - Wiley Online Library
Compartmentalization is an essential feature of all cells. It allows cells to segregate and
coordinate physiological functions in a controlled and ordered manner. Different …

Identification of DypB from Rhodococcus jostii RHA1 as a Lignin Peroxidase

M Ahmad, JN Roberts, EM Hardiman, R Singh… - Biochemistry, 2011 - ACS Publications
Rhodococcus jostii RHA1, a polychlorinated biphenyl-degrading soil bacterium whose
genome has been sequenced, shows lignin degrading activity in two recently developed …

Structural basis of enzyme encapsulation into a bacterial nanocompartment

M Sutter, D Boehringer, S Gutmann… - Nature structural & …, 2008 - nature.com
Compartmentalization is an important organizational feature of life. It occurs at varying levels
of complexity ranging from eukaryotic organelles and the bacterial microcompartments, to …

Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays

SV Gordon, R Brosch, A Billault, T Garnier… - Molecular …, 1999 - Wiley Online Library
Whole‐genome comparisons of the tubercle bacilli were undertaken using ordered bacterial
artificial chromosome (BAC) libraries of Mycobacterium tuberculosis and the vaccine strain …

A virus capsid‐like nanocompartment that stores iron and protects bacteria from oxidative stress

CA McHugh, J Fontana, D Nemecek, N Cheng… - The EMBO …, 2014 - embopress.org
Living cells compartmentalize materials and enzymatic reactions to increase metabolic
efficiency. While eukaryotes use membrane‐bound organelles, bacteria and archaea rely …

The capsule of Mycobacterium tuberculosis and its implications for pathogenicity

M Daffe, G Etienne - Tubercle and lung disease, 1999 - Elsevier
Mycobacterium tuberculosis, one of the most prevalent causes of death worldwide, is a
facultative intracellular parasite that invades and persists within the macrophages. Within …

Encapsulin cargo loading: progress and potential

JA Jones, R Benisch, TW Giessen - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Encapsulins are a recently discovered class of prokaryotic self-assembling icosahedral
protein nanocompartments measuring between 24 and 42 nm in diameter, capable of …

Hypoxic Response of Mycobacterium tuberculosis Studied by Metabolic Labeling and Proteome Analysis of Cellular and Extracellular Proteins

I Rosenkrands, RA Slayden, J Crawford… - Journal of …, 2002 - Am Soc Microbiol
The events involved in the establishment of a latent infection with Mycobacterium
tuberculosis are not fully understood, but hypoxic conditions are generally believed to be the …

Assembly in vitro of Rhodococcus jostii RHA1 encapsulin and peroxidase DypB to form a nanocompartment

R Rahmanpour, TDH Bugg - The FEBS journal, 2013 - Wiley Online Library
Rhodococcus jostii RHA1 peroxidase DypB has been recently identified as a bacterial lignin
peroxidase. The dypB gene is cotranscribed with a gene encoding an encapsulin protein …