Porcine epidemic diarrhea virus: An updated overview of virus epidemiology, virulence variation patterns and virus–host interactions

Y Zhang, Y Chen, J Zhou, X Wang, L Ma, J Li, L Yang… - Viruses, 2022 - mdpi.com
The porcine epidemic diarrhea virus (PEDV) is a member of the coronavirus family, causing
deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant …

Porcine epidemic diarrhea virus: Molecular mechanisms of attenuation and vaccines

Z Li, Z Ma, Y Li, S Gao, S Xiao - Microbial pathogenesis, 2020 - Elsevier
Porcine epidemic diarrhea virus (PEDV) causes an emerging and re-emerging coronavirus
disease characterized by vomiting, acute diarrhea, dehydration, and up to 100% mortality in …

[HTML][HTML] Male predisposition to severe COVID-19: Review of evidence and potential therapeutic prospects

DO Acheampong, IK Barffour, A Boye… - Biomedicine & …, 2020 - Elsevier
The severe form of COVID-19 has significant sex disparities, with high fatalities commonly
reported among males than females. The incidence of COVID-19 has also been higher in …

Porcine intestinal enteroids: a new model for studying enteric coronavirus porcine epidemic diarrhea virus infection and the host innate response

L Li, F Fu, S Guo, H Wang, X He, M Xue, L Yin… - Journal of …, 2019 - Am Soc Microbiol
Porcine epidemic diarrhea virus (PEDV), a member of the group of alphacoronaviruses, is
the pathogen of a highly contagious gastrointestinal swine disease. The elucidation of the …

Genome-scale CRISPR screen identifies TRIM2 and SLC35A1 associated with porcine epidemic diarrhoea virus infection

J Wang, H Liu, Y Yang, Y Tan, L Sun, Z Guo… - International Journal of …, 2023 - Elsevier
Porcine epidemic diarrhoea (PED) caused by the porcine epidemic diarrhoea virus (PEDV)
is the most devastating disease in the global pig industry due to its high mortality rate in …

Downregulation of miR-218 by porcine reproductive and respiratory syndrome virus facilitates viral replication via inhibition of type I interferon responses

L Zhang, L Zhang, Y Pan, J Gao, Y Xu, X Li… - Journal of Biological …, 2021 - ASBMB
Porcine reproductive and respiratory syndrome virus (PRRSV) is a devastating pathogen in
the swine industry worldwide. miRNAs are reported to be involved in virus–host interaction …

Integrin αvβ3 enhances replication of porcine epidemic diarrhea virus on Vero E6 and porcine intestinal epithelial cells

C Li, M Su, B Yin, D Guo, S Wei, F Kong, L Feng… - Veterinary …, 2019 - Elsevier
The entry mechanism of porcine epidemic diarrhea virus (PEDV) remains unclear,
especially the virus receptor. Our previous study revealed a potential correlation between …

Organoids: a promising new in vitro platform in livestock and veterinary research

SK Kar, JM Wells, ED Ellen, MFW Te Pas, O Madsen… - Veterinary …, 2021 - Springer
Organoids are self-organizing, self-renewing three-dimensional cellular structures that
resemble organs in structure and function. They can be derived from adult stem cells …

Paraoxonase-1 facilitates PRRSV replication by interacting with viral nonstructural protein-9 and inhibiting type I interferon pathway

L Zhang, Y Pan, Y Xu, W Zhang, W Ma, YM Ibrahim… - Viruses, 2022 - mdpi.com
Paraoxonase-1 (PON1), an esterase with specifically paraoxonase activity, has been proven
to be involved in inflammation and infection. Porcine reproductive and respiratory syndrome …

Poly (A)-Binding Protein Cytoplasmic 1 Inhibits Porcine Epidemic Diarrhea Virus Replication by Interacting with Nucleocapsid Protein

T Wu, X Wei, S Zheng, G She, Z Han, Z Xu, Y Cao… - Viruses, 2022 - mdpi.com
Porcine epidemic diarrhea virus (PEDV) is the etiological agent of porcine epidemic
diarrhea (PED) characterized by vomit, watery diarrhea, dehydration and high mortality …