A brief review of influenza virus infection
M Javanian, M Barary, S Ghebrehewet… - Journal of medical …, 2021 - Wiley Online Library
Influenza is an acute viral respiratory infection that affects all age groups and is associated
with high mortality during pandemics, epidemics, and sporadic outbreaks. Nearly 10% of the …
with high mortality during pandemics, epidemics, and sporadic outbreaks. Nearly 10% of the …
Influenza lineage extinction during the COVID-19 pandemic?
M Koutsakos, AK Wheatley, K Laurie, SJ Kent… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic has seen a notable global reduction in influenza cases of both
influenza A and B viruses. In particular, the B/Yamagata lineage has not been isolated from …
influenza A and B viruses. In particular, the B/Yamagata lineage has not been isolated from …
Co-evolution of immunity and seasonal influenza viruses
AX Han, SPJ de Jong, CA Russell - Nature Reviews Microbiology, 2023 - nature.com
Seasonal influenza viruses cause recurring global epidemics by continually evolving to
escape host immunity. The viral constraints and host immune responses that limit and drive …
escape host immunity. The viral constraints and host immune responses that limit and drive …
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses
Abstract Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and
infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross …
infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross …
TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes
H Limburg, A Harbig, D Bestle, DA Stein… - Journal of …, 2019 - Am Soc Microbiol
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus
infectivity and spread. We previously demonstrated in vitro that the transmembrane protease …
infectivity and spread. We previously demonstrated in vitro that the transmembrane protease …
Is a universal influenza virus vaccine possible?
R Nachbagauer, P Palese - Annual review of medicine, 2020 - annualreviews.org
Influenza viruses remain a severe burden to human health because of their contribution to
overall morbidity and mortality. Current seasonal influenza virus vaccines do not provide …
overall morbidity and mortality. Current seasonal influenza virus vaccines do not provide …
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity
Immunization with the inactivated influenza vaccine (IIV) remains the most effective strategy
to combat seasonal influenza infections. IIV activates B cells and T follicular helper (TFH) …
to combat seasonal influenza infections. IIV activates B cells and T follicular helper (TFH) …
Harnessing the power of T cells: the promising hope for a universal influenza vaccine
EB Clemens, C Van de Sandt, SS Wong, LM Wakim… - Vaccines, 2018 - mdpi.com
Next-generation vaccines that utilize T cells could potentially overcome the limitations of
current influenza vaccines that rely on antibodies to provide narrow subtype-specific …
current influenza vaccines that rely on antibodies to provide narrow subtype-specific …
Downregulation of MHC class I expression by influenza A and B viruses
Manipulation of the MHC-I presentation pathway, and thus limiting MHC-I cell surface
expression, is used by many viruses to evade immune recognition. In particular …
expression, is used by many viruses to evade immune recognition. In particular …
Influenza virus infections and cellular kinases
R Meineke, GF Rimmelzwaan, H Elbahesh - Viruses, 2019 - mdpi.com
Influenza A viruses (IAVs) are a major cause of respiratory illness and are responsible for
yearly epidemics associated with more than 500,000 annual deaths globally. Novel IAVs …
yearly epidemics associated with more than 500,000 annual deaths globally. Novel IAVs …