Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

Recent advances in microbial ecology and synthetic biology have the potential to mitigate
damage caused by anthropogenic activities that are deleteriously impacting Earth's soil …

Microbial biocontainment is an essential goal for engineering safe, next-generation living
therapeutics. However, the genetic stability of biocontainment circuits, including kill switches …

Phenylketonuria (PKU) is a genetic disease that is characterized by an inability to
metabolize phenylalanine (Phe), which can result in neurotoxicity. To provide a potential …

Nature uses a limited, conservative set of amino acids to synthesize proteins. The ability to
genetically encode an expanded set of building blocks with new chemical and physical …

Genetically modified microorganisms (GMMs) can enable a wide range of important
applications including environmental sensing and responsive engineered living materials …

CRISPR–Cas9 delivery by adeno-associated virus (AAV) holds promise for gene therapy
but faces critical barriers on account of its potential immunogenicity and limited payload …

Our ability to generate bacterial strains with unique and increasingly complex functions has
rapidly expanded in recent times. The capacity for DNA synthesis is increasing and costing …

Engineering the genetic code of an organism has been proposed to provide a firewall from
natural ecosystems by preventing viral infections and gene transfer,,,,–. However, numerous …

Genetic engineering applications in the field of biofuel are rapidly expanding due to their
potential to boost biomass productivity while lowering its cost and enhancing its quality …