The Landscape of long noncoding RNA classification
GS Laurent, C Wahlestedt, P Kapranov - Trends in genetics, 2015 - cell.com
Advances in the depth and quality of transcriptome sequencing have revealed many new
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …
[HTML][HTML] lincRNAs: genomics, evolution, and mechanisms
Long intervening noncoding RNAs (lincRNAs) are transcribed from thousands of loci in
mammalian genomes and might play widespread roles in gene regulation and other cellular …
mammalian genomes and might play widespread roles in gene regulation and other cellular …
Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation
NA O'Leary, MW Wright, JR Brister, S Ciufo… - Nucleic acids …, 2016 - academic.oup.com
The RefSeq project at the National Center for Biotechnology Information (NCBI) maintains
and curates a publicly available database of annotated genomic, transcript, and protein …
and curates a publicly available database of annotated genomic, transcript, and protein …
An atlas of active enhancers across human cell types and tissues
Enhancers control the correct temporal and cell-type-specific activation of gene expression
in multicellular eukaryotes. Knowing their properties, regulatory activity and targets is crucial …
in multicellular eukaryotes. Knowing their properties, regulatory activity and targets is crucial …
Analysis of RNA-Seq data using TopHat and Cufflinks
S Ghosh, CKK Chan - Plant Bioinformatics: Methods and Protocols, 2016 - Springer
The recent advances in high throughput RNA sequencing (RNA-Seq) have generated huge
amounts of data in a very short span of time for a single sample. These data have required …
amounts of data in a very short span of time for a single sample. These data have required …
[HTML][HTML] Choosing the right tool for the job: RNAi, TALEN, or CRISPR
M Boettcher, MT McManus - Molecular cell, 2015 - cell.com
The most widely used approach for defining gene function is to reduce or completely disrupt
its normal expression. For over a decade, RNAi has ruled the lab, offering a magic bullet to …
its normal expression. For over a decade, RNAi has ruled the lab, offering a magic bullet to …
Landscape of transcription in human cells
Eukaryotic cells make many types of primary and processed RNAs that are found either in
specific subcellular compartments or throughout the cells. A complete catalogue of these …
specific subcellular compartments or throughout the cells. A complete catalogue of these …
Chemical ecology of endophytic fungi: origins of secondary metabolites
S Kusari, C Hertweck, M Spiteller - Chemistry & biology, 2012 - cell.com
Endophytes constitute a remarkably multifarious group of microorganisms ubiquitous in
plants and maintain an imperceptible association with their hosts for at least a part of their …
plants and maintain an imperceptible association with their hosts for at least a part of their …
Dual RNA-seq of pathogen and host
AJ Westermann, SA Gorski, J Vogel - Nature Reviews Microbiology, 2012 - nature.com
A comprehensive understanding of host–pathogen interactions requires a knowledge of the
associated gene expression changes in both the pathogen and the host. Traditional, probe …
associated gene expression changes in both the pathogen and the host. Traditional, probe …
RNA-Seq: a revolutionary tool for transcriptomics
RNA-Seq is a recently developed approach to transcriptome profiling that uses deep-
sequencing technologies. Studies using this method have already altered our view of the …
sequencing technologies. Studies using this method have already altered our view of the …