Photoacoustic (PA) imaging is an emerging biomedical imaging technique with the features
of non‐invasiveness and non‐ionization. It takes advantage of the photothermal effect of PA …

Heterogeneous cells are the main feature of tumors with unique genetic and phenotypic
characteristics, which can stimulate differentially the progression, metastasis, and drug …

Vital biomacromolecules, such as RNA, DNA, polysaccharides and proteins, are
synthesized inside cells via the polymerization of small biomolecules to support and multiply …

Cathepsin B (CTSB) is a lysosomal protease that is overexpressed in the early stage of
many cancer types. Precise evaluation of CTSB expression in vivo may provide a promising …

Organic semiconductors (OSCs) have emerged as promising materials for a variety of
organic electronic devices due to their unique combination of electrical conductivity …

Fluorescence imaging in the second near-infrared region (NIR-II) shows great potentials in
intravital imaging and analysis due to its high penetration depth and low photo-damage …

Acoustic-based imaging techniques, including ultrasonography and photoacoustic imaging,
are powerful noninvasive approaches for tumor imaging owing to sound transmission …

With high efficiency, mild conditions, and rapid reaction rate, click reactions have garnered
much attention in the field of bioimaging since proposed by Sharpless et al. in 2001 (Angew …

Recently, second near-infrared (NIR-II) fluorescent imaging has been widely applied in
biomedical diagnosis, due to its high spatiotemporal resolution and deep tissue penetration …

The pH environment in cancer cells has been demonstrated to display vital influences on the
therapeutic effect of photodynamic therapy (PDT). It is very interesting to develop pH …