The molecular mechanisms underlying the regulation of the biological activity of corticotropin-releasing hormone receptors: implications for physiology and …

EW Hillhouse, DK Grammatopoulos - Endocrine reviews, 2006 - academic.oup.com
The CRH receptor (CRH-R) is a member of the secretin family of G protein-coupled
receptors. Wide expression of CRH-Rs in the central nervous system and periphery ensures …

The interplay between oxytocin and the CRF system: regulation of the stress response

J Winter, B Jurek - Cell and tissue research, 2019 - Springer
Oxytocin (OT) has drawn the attention of researchers since 1930. Since then, many aspects
of oxytocin have been uncovered, such as reproductive functions, dampening anxiety …

Functional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonists

DK Grammatopoulos, GP Chrousos - Trends in Endocrinology & …, 2002 - cell.com
Corticotropin-releasing hormone (CRH) plays a major role in coordinating the behavioral,
endocrine, autonomic and immune responses to stress. CRH and CRH-related peptides and …

Corticotropin-releasing hormone-binding protein and stress: from invertebrates to humans

KD Ketchesin, GS Stinnett, AF Seasholtz - Stress, 2017 - Taylor & Francis
Corticotropin-releasing hormone (CRH) is a key regulator of the stress response. This
peptide controls the hypothalamic-pituitary-adrenal (HPA) axis as well as a variety of …

Priming of long-term potentiation in mouse hippocampus by corticotropin-releasing factor and acute stress: implications for hippocampus-dependent learning

T Blank, I Nijholt, K Eckart, J Spiess - Journal of neuroscience, 2002 - Soc Neuroscience
In the present experiments, we characterized the action of human/rat corticotropin-releasing
factor (h/rCRF) and acute stress (1 hr of immobilization) on hippocampus-dependent …

Corticotropin-releasing factor receptors couple to multiple G-proteins to activate diverse intracellular signaling pathways in mouse hippocampus: role in neuronal …

T Blank, I Nijholt, DK Grammatopoulos… - Journal of …, 2003 - Soc Neuroscience
Corticotropin-releasing factor (CRF) exerts a key neuroregulatory control on stress
responses in various regions of the mammalian brain, including the hippocampus. Using …

Differential actions of peripheral corticotropin-releasing factor (CRF), urocortin II, and urocortin III on gastric emptying and colonic transit in mice: role of CRF receptor …

V Martı́nez, L Wang, JE Rivier, W Vale… - Journal of Pharmacology …, 2002 - ASPET
Peripheral CRF inhibits gastric emptying and stimulates colonic motor function in rats. We
investigated the role of CRF1and CRF2 receptors in ip CRF-induced alterations of gut transit …

[PDF][PDF] CRH-BP: the regulation and function of a phylogenetically conserved binding protein

NJ Westphal, AF Seasholtz - Front Biosci, 2006 - researchgate.net
CRH family of peptides and binding partners 2.1. CRH family of peptides 2.2. CRH
Receptors 2.3. CRH Binding Protein 3. CRH-BP evolutionary conservation 4. CRH-BP …

[HTML][HTML] Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF2-deficient mice

C Todorovic, T Sherrin, M Pitts, C Hippel… - …, 2009 - nature.com
The neuropeptide corticotropin-releasing factor (CRF) plays a critical role in the proper
functioning of the stress response system through its actions on its receptors, CRF receptor 1 …

Tonic modulation of anxiety-like behavior by corticotropin-releasing factor (CRF) type 1 receptor (CRF1) within the medial prefrontal cortex (mPFC) in male mice: role …

TT Miguel, KS Gomes, RL Nunes-de-Souza - Hormones and behavior, 2014 - Elsevier
The medial prefrontal cortex (mPFC) and the neuropeptide corticotropin-releasing factor
(CRF) have recently been receiving more attention from those interested in the neurobiology …