Assembly of the mycobacterial cell wall

M Jankute, JAG Cox, J Harrison… - Annual review of …, 2015 - annualreviews.org
Mycobacterium tuberculosis remains one of the most successful bacterial pathogens,
claiming over 1.3 million lives worldwide in 2013. The emergence of multidrug-resistant and …

Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target

KA Abrahams, GS Besra - Parasitology, 2018 - cambridge.org
Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB), is recognized
as a global health emergency as promoted by the World Health Organization. Over 1 million …

The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system

SM Batt, DE Minnikin, GS Besra - Biochemical Journal, 2020 - portlandpress.com
Tuberculosis, caused by the pathogenic bacterium Mycobacterium tuberculosis (Mtb), is the
leading cause of death from an infectious disease, with a mortality rate of over a million …

Contextual control of skin immunity and inflammation by Corynebacterium

VK Ridaura, N Bouladoux, J Claesen… - Journal of Experimental …, 2018 - rupress.org
How defined microbes influence the skin immune system remains poorly understood. Here
we demonstrate that Corynebacteria, dominant members of the skin microbiota, promote a …

Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host–pathogen interaction

AK Mishra, NN Driessen, BJ Appelmelk… - FEMS microbiology …, 2011 - academic.oup.com
Approximately one third of the world's population is infected with Mycobacterium
tuberculosis, the causative agent of tuberculosis. This bacterium has an unusual lipid-rich …

MmpL genes are associated with mycolic acid metabolism in mycobacteria and corynebacteria

C Varela, D Rittmann, A Singh, K Krumbach, K Bhatt… - Chemistry & biology, 2012 - cell.com
Mycolic acids are vital components of the cell wall of the tubercle bacillus Mycobacterium
tuberculosis and are required for viability and virulence. While mycolic acid biosynthesis is …

Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis

D Kaur, ME Guerin, H Škovierová, PJ Brennan… - Advances in applied …, 2009 - Elsevier
The re-emergence of tuberculosis in its present-day manifestations–single, multiple and
extensive drug-resistant forms and as HIV-TB coinfections–has resulted in renewed …

The cell envelope glycoconjugates of Mycobacterium tuberculosis

SK Angala, JM Belardinelli, E Huc-Claustre… - Critical reviews in …, 2014 - Taylor & Francis
Tuberculosis (TB) remains the second most common cause of death due to a single
infectious agent. The cell envelope of Mycobacterium tuberculosis (Mtb), the causative agent …

Transporters involved in the biogenesis and functionalization of the mycobacterial cell envelope

M Jackson, CM Stevens, L Zhang, HI Zgurskaya… - Chemical …, 2020 - ACS Publications
The biology of mycobacteria is dominated by a complex cell envelope of unique composition
and structure and of exceptionally low permeability. This cell envelope is the basis of many …

[HTML][HTML] Antibiotics and resistance: the two-sided coin of the mycobacterial cell wall

SM Batt, CE Burke, AR Moorey, GS Besra - The Cell Surface, 2020 - Elsevier
Mycobacterium tuberculosis, the bacterium responsible for tuberculosis, is the global
leading cause of mortality from an infectious agent. Part of this success relies on the unique …