Mutualistic interplay between bacteriophages and bacteria in the human gut
Bacteriophages (phages) are often described as obligate predators of their bacterial hosts,
and phage predation is one of the leading forces controlling the density and distribution of …
and phage predation is one of the leading forces controlling the density and distribution of …
The logic of virus evolution
Viruses are obligate intracellular parasites. Despite their dependence on host cells, viruses
are evolutionarily autonomous, with their own genomes and evolutionary trajectories locked …
are evolutionarily autonomous, with their own genomes and evolutionary trajectories locked …
Identification of mobile genetic elements with geNomad
Identifying and characterizing mobile genetic elements in sequencing data is essential for
understanding their diversity, ecology, biotechnological applications and impact on public …
understanding their diversity, ecology, biotechnological applications and impact on public …
Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome
Bacteriophages have important roles in the ecology of the human gut microbiome but are
under-represented in reference databases. To address this problem, we assembled the …
under-represented in reference databases. To address this problem, we assembled the …
Pharokka: a fast scalable bacteriophage annotation tool
In recent years, there has been an increasing interest in bacteriophages, which has led to
growing numbers of bacteriophage genomic sequences becoming available. Consequently …
growing numbers of bacteriophage genomic sequences becoming available. Consequently …
[HTML][HTML] Expansion of the global RNA virome reveals diverse clades of bacteriophages
High-throughput RNA sequencing offers broad opportunities to explore the Earth RNA
virome. Mining 5,150 diverse metatranscriptomes uncovered> 2.5 million RNA virus contigs …
virome. Mining 5,150 diverse metatranscriptomes uncovered> 2.5 million RNA virus contigs …
Expanding known viral diversity in the healthy infant gut
The gut microbiome is shaped through infancy and impacts the maturation of the immune
system, thus protecting against chronic disease later in life. Phages, or viruses that infect …
system, thus protecting against chronic disease later in life. Phages, or viruses that infect …
Interrogating the viral dark matter of the rumen ecosystem with a global virome database
The diverse rumen virome can modulate the rumen microbiome, but it remains largely
unexplored. Here, we mine 975 published rumen metagenomes for viral sequences, create …
unexplored. Here, we mine 975 published rumen metagenomes for viral sequences, create …
Thousands of previously unknown phages discovered in whole-community human gut metagenomes
Background Double-stranded DNA bacteriophages (dsDNA phages) play pivotal roles in
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
Characterization of crAss-like phage isolates highlights Crassvirales genetic heterogeneity and worldwide distribution
MD Ramos-Barbero, C Gómez-Gómez… - Nature …, 2023 - nature.com
Crassvirales (crAss-like phages) are an abundant group of human gut-specific
bacteriophages discovered in silico. The use of crAss-like phages as human fecal indicators …
bacteriophages discovered in silico. The use of crAss-like phages as human fecal indicators …