Background: Cancer will replace cardiovascular diseases as the most frequent cause of
death. Therefore, the goals of cancer treatment are prevention strategies and early detection …

Ultrasound shear wave elasticity imaging is a valuable tool for quantifying the elastic
properties of tissue. Typically, the shear wave velocity is derived and mapped to an elasticity …

Tissue stiffness is related to soft tissue pathologies and can be assessed through palpation
or via clinical imaging systems, eg, ultrasound or magnetic resonance imaging. Typically …

Objective: Soft tissue deformation and ruptures complicate needle placement. However,
ruptures at tissue interfaces also contain information which helps physicians to navigate …

Objective: Optical coherence elastography (OCE) allows for high resolution analysis of
elastic tissue properties. However, due to the limited penetration of light into tissue …

Purpose Elasticity of soft tissue provides valuable information to physicians during treatment
and diagnosis of diseases. A number of approaches have been proposed to estimate tissue …

The distinction between malignant and benign tumors is essential to the treatment of cancer.
The tissue's elasticity can be used as an indicator for the required tissue characterization …

Mechanical properties of tissue provide valuable information for identifying lesions. One
approach to obtain quantitative estimates of elastic properties is shear wave elastography …

Purpose Needle placement is a challenging problem for applications such as biopsy or
brachytherapy. Tip force sensing can provide valuable feedback for needle navigation …

This thesis analyzes different aspects of image guidance in robotic radiosurgery considering
the modalities ultrasound imaging and optical coherence tomography (OCT). Robotic …