G9a in Cancer: Mechanisms, Therapeutic Advancements, and Clinical Implications

Y Ni, M Shi, L Liu, D Lin, H Zeng, C Ong, Y Wang - Cancers, 2024 - mdpi.com
Simple Summary In this review, we have summarized the crucial role of G9a in cellular
biology and disease. By synthesizing recent research discoveries, we delve into the …

Factors determining the sensitivity to proteasome inhibitors of multiple myeloma cells

M Pelon, P Krzeminski, Z Tracz-Gaszewska… - Frontiers in …, 2024 - frontiersin.org
Multiple myeloma is an incurable cancer that originates from antibody-producing plasma
cells. It is characterized by an intrinsic ability to produce large amounts of immunoglobulin …

Understanding DNA Epigenetics by Means of Raman/SERS Analysis for Cancer Detection

L David, A Onaciu, V Toma, RM Borșa, C Moldovan… - Biosensors, 2024 - mdpi.com
This study delves into the intricate interaction between DNA and nanosystems, exploring its
potential implications for biomedical applications. The focus lies in understanding the …

[HTML][HTML] Gene signatures to therapeutics: Assessing the potential of ivermectin against t (4; 14) multiple myeloma

Y Song, HJ Zhang, X Song, J Geng, HY Li… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Multiple myeloma (MM) is a terminal differentiated B-cell tumor disease
characterized by clonal proliferation of malignant plasma cells and excessive levels of …

Ginsenoside Rg1 Inhibits Multiple Myeloma and Overcomes Bortezomib Resistance Through AMPK-mTOR Pathway

L Lin, D Chen, S Li, T Wang - Heliyon, 2024 - cell.com
Background The resistance of multiple myeloma (MM) to bortezomib (BTZ) has brought
multiple challenges to its clinical use. Numerous ginsenosides have potential anti-tumor …

Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma

C Bandini, E Mereu, T Paradzik, M Labrador… - … Hematology & Oncology, 2023 - Springer
Background Multiple myeloma (MM) is an incurable plasma cell malignancy, accounting for
approximately 1% of all cancers. Despite recent advances in the treatment of MM, due to the …