Significance: Surgery is often paramount in the management of many solid organ
malignancies because optimal resection is a major factor in disease-specific survival …

Worldwide, various guidelines recommend what constitutes an adequate margin of excision
for invasive breast cancer or for ductal carcinoma-in-situ (DCIS). We evaluated the use of …

Since the inception of optical coherence tomography (OCT), advancements in imaging
system design and handheld probes have allowed for numerous advancements in disease …

Breast density is a strong predictor of the failure of mammography screening to detect breast
cancer and is a strong predictor of the risk of developing breast cancer. The many imaging …

Background: The most common type of breast cancer is the ductal type (IDC), followed by
lobular type (ILC). Surgery is the main therapy for early-stage breast cancer. Adjuvant …

Purpose: Although surgical therapy for breast cancer has become less radical, intrasurgical
placement of drains and the use of compression bandages is still standard practice …

Background Management of breast ductal carcinoma in situ (DCIS) has various approaches
with distinct institutional specific practice. Here, we review DCIS management in a single …

Background Current guidelines state that “no ink on tumor” constitutes adequate surgical
margins for lumpectomy specimens. However, there remains uncertainty when tumor is …

Purpose: The aim of this study was to investigate the value of intraoperative ultrasound in
breast-conserving operations and to compare it with standard procedures. Methods: For this …

The SUCCESS-A trial is a prospective, multicenter, phase III clinical trial for high-risk primary
breast cancer. It compares disease-free survival after randomization in patients treated with …