Contributions of 3D chromatin structure to cell-type-specific gene regulation

M Schaeffer, M Nollmann - Current opinion in genetics & development, 2023 - Elsevier
Eukaryotic genomes are organized in 3D in a multiscale manner, and different mechanisms
acting at each of these scales can contribute to transcriptional regulation. However, the large …

Activation of Stimulator of Interferon Genes (STING): Promising Strategy to Overcome Immune Resistance in Prostate Cancer

M Alnukhali, O Altabbakh, AA Farooqi… - Current medicinal …, 2024 - benthamdirect.com
Prostate cancer (PCa) is the most frequent and second-lethal cancer among men. Despite
considerable efforts to explore treatments like autologous cellular immunotherapy and …

Chromosome compartmentalization: causes, changes, consequences, and conundrums

H Li, C Playter, P Das, RP McCord - Trends in Cell Biology, 2024 - cell.com
The spatial segregation of the genome into compartments is a major feature of 3D genome
organization. New data on mammalian chromosome organization across different conditions …

SnapFISH-IMPUTE: an imputation method for multiplexed DNA FISH data

H Yu, D Wu, S Mishra, G Shen, H Sun, M Hu… - Communications …, 2024 - nature.com
Chromatin spatial organization plays a crucial role in gene regulation. Recently developed
and prospering multiplexed DNA FISH technologies enable direct visualization of chromatin …