Current and new generation pneumococcal vaccines

C Feldman, R Anderson - Journal of Infection, 2014 - Elsevier
Pneumococcal polysaccharide vaccines (PPVs) and conjugate vaccines (PCVs), of which
PPV23 and PCV13 are the current front runners, have had a significant, beneficial impact on …

Major histocompatibility complex linked databases and prediction tools for designing vaccines

SP Singh, BN Mishra - Human immunology, 2016 - Elsevier
Presently, the major histocompatibility complex (MHC) is receiving considerable interest
owing to its remarkable role in antigen presentation and vaccine design. The specific …

Peptides-Based Vaccine MP3RT Induced Protective Immunity Against Mycobacterium Tuberculosis Infection in a Humanized Mouse Model

W Gong, Y Liang, J Mi, Z Jia, Y Xue, J Wang… - Frontiers in …, 2021 - frontiersin.org
Background Tuberculosis (TB) is still a global infectious disease that seriously threatens
human beings. The only licensed TB vaccine Bacille Calmette-Guérin (BCG)'s protective …

A chitosan-based nanosystem as pneumococcal vaccine delivery platform

S Robla, M Prasanna, R Varela-Calviño… - Drug Delivery and …, 2021 - Springer
Chitosan-based nanosystems have been described as interesting tools for antigen delivery
and for enhancing the immunogenicity of nasally administered vaccines. As a possible …

IL17eScan: a tool for the identification of peptides inducing IL-17 response

S Gupta, P Mittal, MK Madhu, VK Sharma - Frontiers in immunology, 2017 - frontiersin.org
IL-17 cytokines are pro-inflammatory cytokines and are crucial in host defense against
various microbes. Induction of these cytokines by microbial antigens has been investigated …

A peptide-based vaccine ACP derived from antigens of Mycobacterium tuberculosis induced Th1 response but failed to enhance the protective efficacy of BCG in mice

W Gong, Y Liang, J Mi, Y Xue, J Wang, L Wang… - Indian Journal of …, 2022 - Elsevier
Background Tuberculosis (TB) is a global infectious disease, but there is no ideal vaccine
against TB except the Bacille Calmette-Guérin (BCG) vaccine. Methods Herein, 25 …

Genome based screening of epitope ensemble vaccine candidates against dreadful visceral leishmaniasis using immunoinformatics approach

G Singh, M Pritam, M Banerjee, AK Singh… - Microbial …, 2019 - Elsevier
Visceral leishmaniasis (VL) is a dreadful protozoan disease caused by Leishmania
donovani that severely affects huge populations in tropical and sub-tropical regions. The …

Site-specific conjugation for fully controlled glycoconjugate vaccine preparation

A Pillot, A Defontaine, A Fateh, A Lambert… - Frontiers in …, 2019 - frontiersin.org
Glycoconjugate vaccines are formed by covalently link a carbohydrate antigen to a carrier
protein whose role is to achieve a long lasting immune response directed against the …

Th1 epitope peptides induce protective immunity against Rickettsia rickettsii infection in C3H/HeN mice

P Wang, X Xiong, J Jiao, X Yang, Y Jiang, B Wen… - Vaccine, 2017 - Elsevier
Rickettsia rickettsii is the causative pathogen of Rocky Mountain spotted fever (RMSF). Adr2,
YbgF and OmpB are protective antigens of R. rickettsii. In this study, 90 candidate peptides …

A T-cell epitope-based multi-epitope vaccine designed using human HLA specific T cell epitopes induces a near-sterile immunity against experimental visceral …

A Arya, SK Arora - Vaccines, 2021 - mdpi.com
Visceral leishmaniasis is a neglected tropical disease affecting 12 million people annually.
Even in the second decade of the 21st century, it has remained without an effective vaccine …