Wastewater-based surveillance as a tool for public health action: SARS-CoV-2 and beyond

MD Parkins, BE Lee, N Acosta, M Bautista… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …

Evolution of the SARS-CoV-2 Omicron spike

RJ Parsons, P Acharya - Cell reports, 2023 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern, first identified in November 2021, rapidly spread worldwide and diversified into …

Enabling accurate and early detection of recently emerged SARS-CoV-2 variants of concern in wastewater

N Sapoval, Y Liu, EG Lou, L Hopkins, KB Ensor… - Nature …, 2023 - nature.com
As clinical testing declines, wastewater monitoring can provide crucial surveillance on the
emergence of SARS-CoV-2 variant of concerns (VoCs) in communities. In this paper we …

SARS-CoV-2 diagnostic testing rates determine the sensitivity of genomic surveillance programs

AX Han, A Toporowski, JA Sacks, MD Perkins… - Nature Genetics, 2023 - nature.com
The first step in SARS-CoV-2 genomic surveillance is testing to identify people who are
infected. However, global testing rates are falling as we emerge from the acute health …

Wastewater surveillance uncovers regional diversity and dynamics of SARS-CoV-2 variants across nine states in the USA

RS Fontenele, Y Yang, EM Driver, A Magge… - Science of the Total …, 2023 - Elsevier
Wastewater-based epidemiology (WBE) is a non-invasive and cost-effective approach for
monitoring the spread of a pathogen within a community. WBE has been adopted as one of …

Considerations and Opportunities for Probe Capture Enrichment Sequencing of Emerging Viruses from Wastewater

RS Kantor, M Jiang - Environmental Science & Technology, 2024 - ACS Publications
Until recently, wastewater-based monitoring for pathogens of public health concern primarily
used PCR-based quantification methods and targeted sequencing for specific pathogens …

Online dashboards for SARS-CoV-2 wastewater-based epidemiology

D Focosi, PG Spezia, F Maggi - Future Microbiology, 2024 - Taylor & Francis
Aim: Wastewater-based epidemiology (WBE) is increasingly used to monitor pandemics. In
this manuscript, we review methods and limitations of WBE, as well as their online …

Metagenomic sequencing detects human respiratory and enteric viruses in air samples collected from congregate settings

NR Minor, MD Ramuta, MR Stauss, OE Harwood… - Scientific reports, 2023 - nature.com
Innovative methods for evaluating virus risk and spread, independent of test-seeking
behavior, are needed to improve routine public health surveillance, outbreak response, and …

Wastewater genomic surveillance captures early detection of Omicron in Utah

P Gupta, S Liao, M Ezekiel, N Novak… - Microbiology …, 2023 - Am Soc Microbiol
Wastewater-based epidemiology has emerged as a powerful public health tool to trace new
outbreaks, detect trends in infection, and provide an early warning of COVID-19 community …

bettercallsal: better calling of Salmonella serotypes from enrichment cultures using shotgun metagenomic profiling and its application in an outbreak setting

K Konganti, E Reed, M Mammel, T Kayikcioglu… - Frontiers in …, 2023 - frontiersin.org
Most current Salmonella subtyping analyses rely on whole genome sequencing (WGS),
which focuses on the high-resolution analysis of single genomes or multiple single genomes …