Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively
associated with cardiovascular and neurodegenerative diseases. However, findings from …

Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture,
vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute …

Coronary artery disease is the leading global cause of mortality. Long recognized to be
heritable, recent advances have started to unravel the genetic architecture of the disease …

Macroalgae or seaweed are relative un-explored and promising sources of novel molecules
for the food industry including peptides and carbohydrates for their use as functional foods …

Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

The phospholipase A2 (PLA2) superfamily contains more than 50 enzymes in mammals that
are subdivided into several distinct families on a structural and biochemical basis. In …

Coronary artery disease (CAD) arising from atherosclerosis is a leading cause of death and
morbidity worldwide. The underlying pathogenesis involves an imbalanced lipid metabolism …

Atherosclerosis is a chronic inflammatory disease associated with cardiovascular
dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke …

According to the traditional view, atherosclerosis results from a passive buildup of
cholesterol in the artery wall. Yet, burgeoning evidence implicates inflammation and immune …

1.1. Discovery of the Phospholipase A2 Superfamily Phospholipases represent one of the
earliest enzyme activities to be identified and studied, and the phospholipase A2 (PLA2) …