[HTML][HTML] Post-translational protein acetylation: an elegant mechanism for bacteria to dynamically regulate metabolic functions
Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …
to an existing proteome. The large number of known PTMs highlights the many ways that …
Proteomics and integrative omic approaches for understanding host–pathogen interactions and infectious diseases
Organisms are constantly exposed to microbial pathogens in their environments. When a
pathogen meets its host, a series of intricate intracellular interactions shape the outcome of …
pathogen meets its host, a series of intricate intracellular interactions shape the outcome of …
Acylation of biomolecules in prokaryotes: a widespread strategy for the control of biological function and metabolic stress
KL Hentchel… - … and Molecular Biology …, 2015 - Am Soc Microbiol
Acylation of biomolecules (eg, proteins and small molecules) is a process that occurs in cells
of all domains of life and has emerged as a critical mechanism for the control of many …
of all domains of life and has emerged as a critical mechanism for the control of many …
Regulation, function, and detection of protein acetylation in bacteria
VJ Carabetta, IM Cristea - Journal of bacteriology, 2017 - Am Soc Microbiol
ABSTRACT N ε-Lysine acetylation is now recognized as an abundant posttranslational
modification (PTM) that influences many essential biological pathways. Advancements in …
modification (PTM) that influences many essential biological pathways. Advancements in …
Mechanisms, detection, and relevance of protein acetylation in prokaryotes
DG Christensen, JT Baumgartner, X Xie, KM Jew… - MBio, 2019 - Am Soc Microbiol
Posttranslational modification of a protein, either alone or in combination with other
modifications, can control properties of that protein, such as enzymatic activity, localization …
modifications, can control properties of that protein, such as enzymatic activity, localization …
[HTML][HTML] Changes in the Acetylome and Succinylome of Bacillus subtilis in Response to Carbon Source
S Kosono, M Tamura, S Suzuki, Y Kawamura… - PloS one, 2015 - journals.plos.org
Lysine residues can be post-translationally modified by various acyl modifications in
bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and …
bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and …
[HTML][HTML] Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn's disease
Lysine acetylation (Kac), an abundant post-translational modification (PTM) in prokaryotes,
regulates various microbial metabolic pathways. However, no studies have examined …
regulates various microbial metabolic pathways. However, no studies have examined …
[HTML][HTML] Acetylation of Lysine 201 Inhibits the DNA-Binding Ability of PhoP to Regulate Salmonella Virulence
J Ren, Y Sang, Y Tan, J Tao, J Ni, S Liu, X Fan… - PLoS …, 2016 - journals.plos.org
The two-component system PhoP-PhoQ is highly conserved in bacteria and regulates
virulence in response to various signals for bacteria within the mammalian host. Here, we …
virulence in response to various signals for bacteria within the mammalian host. Here, we …
Protein acetylation and its role in bacterial virulence
Protein acetylation is a universal post-translational modification which is found in both
eukaryotes and prokaryotes. This process is achieved enzymatically by the protein …
eukaryotes and prokaryotes. This process is achieved enzymatically by the protein …
[HTML][HTML] Acetylation of glucosyltransferases regulates Streptococcus mutans biofilm formation and virulence
Q Ma, Y Pan, Y Chen, S Yu, J Huang, Y Liu… - PLoS …, 2021 - journals.plos.org
Lysine acetylation is a frequently occurring post-translational modification (PTM), emerging
as an important metabolic regulatory mechanism in prokaryotes. This process is achieved …
as an important metabolic regulatory mechanism in prokaryotes. This process is achieved …