Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …

Organisms are constantly exposed to microbial pathogens in their environments. When a
pathogen meets its host, a series of intricate intracellular interactions shape the outcome of …

Acylation of biomolecules (eg, proteins and small molecules) is a process that occurs in cells
of all domains of life and has emerged as a critical mechanism for the control of many …

ABSTRACT N ε-Lysine acetylation is now recognized as an abundant posttranslational
modification (PTM) that influences many essential biological pathways. Advancements in …

Posttranslational modification of a protein, either alone or in combination with other
modifications, can control properties of that protein, such as enzymatic activity, localization …

Lysine residues can be post-translationally modified by various acyl modifications in
bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and …

Lysine acetylation (Kac), an abundant post-translational modification (PTM) in prokaryotes,
regulates various microbial metabolic pathways. However, no studies have examined …

The two-component system PhoP-PhoQ is highly conserved in bacteria and regulates
virulence in response to various signals for bacteria within the mammalian host. Here, we …

Protein acetylation is a universal post-translational modification which is found in both
eukaryotes and prokaryotes. This process is achieved enzymatically by the protein …

Lysine acetylation is a frequently occurring post-translational modification (PTM), emerging
as an important metabolic regulatory mechanism in prokaryotes. This process is achieved …