It is well established that early life environmental signals, including nutrition, set the stage for
long-term health and disease risk–effects that span multiple generations. This relationship …

Developmental programming predisposes offspring to metabolic, behavioural and
reproductive dysfunction in adult life. Evidence is accumulating that ageing phenotype and …

Parental nutrition can impact the health of future generations, programming the offspring for
the development of diseases. The developing germ cells of the offspring could be damaged …

The basis of the pathogenesis of male infertility is the processes of peroxide oxidation of
biological substrates, especially lipids and proteins. By destroying the sperm membrane …

Background Maternal overnutrition including pre-pregnancy, pregnancy and lactation
promotes a lipotoxic insult leading to metabolic dysfunction in offspring. Diet-induced obesity …

Objective This study investigated the effect of maternal obesity on aged-male offspring liver
phenotype and hepatic expression of a programmed miRNA. Methods A mouse model …

Adipocyte size (AS) shows asymmetric distribution related to current metabolic state, eg,
adipogenesis or lipolysis. We profiled AS distribution using different statistical approaches in …

The present work aimed to study the changes caused by maternal obesity and overnutrition
in both the quality and function of spermatozoa of the offspring. To this end, female rats …

Being overweight and obesity are world health problems, with a higher prevalence in
women, defined as abnormal or excessive fat accumulation that increases the risk of chronic …

This study aimed to investigate the effects of maternal unhealthy nutrition on the
reproductive functions of female and male adult offspring. This was an animal study carried …